Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes

Gene pairs that are coexpressed across various environmental conditions in multiple species suggest functional similarity. Here the authors analyze patterns of gene expression co-evolution across diverse eukaryotes, and identify hundreds of protein complexes and pathways whose gene expression levels...

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Main Authors: Trevor Martin, Hunter B. Fraser
Format: Article
Language:English
Published: Nature Portfolio 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07436-y
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author Trevor Martin
Hunter B. Fraser
author_facet Trevor Martin
Hunter B. Fraser
author_sort Trevor Martin
collection DOAJ
description Gene pairs that are coexpressed across various environmental conditions in multiple species suggest functional similarity. Here the authors analyze patterns of gene expression co-evolution across diverse eukaryotes, and identify hundreds of protein complexes and pathways whose gene expression levels have co-evolved since their ancient divergence.
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spelling doaj.art-a482a7902ada43c7af2bfcb1d28f40be2022-12-21T19:27:49ZengNature PortfolioNature Communications2041-17232018-11-01911910.1038/s41467-018-07436-yComparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotesTrevor Martin0Hunter B. Fraser1Department of Biology, Stanford UniversityDepartment of Biology, Stanford UniversityGene pairs that are coexpressed across various environmental conditions in multiple species suggest functional similarity. Here the authors analyze patterns of gene expression co-evolution across diverse eukaryotes, and identify hundreds of protein complexes and pathways whose gene expression levels have co-evolved since their ancient divergence.https://doi.org/10.1038/s41467-018-07436-y
spellingShingle Trevor Martin
Hunter B. Fraser
Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
Nature Communications
title Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
title_full Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
title_fullStr Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
title_full_unstemmed Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
title_short Comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
title_sort comparative expression profiling reveals widespread coordinated evolution of gene expression across eukaryotes
url https://doi.org/10.1038/s41467-018-07436-y
work_keys_str_mv AT trevormartin comparativeexpressionprofilingrevealswidespreadcoordinatedevolutionofgeneexpressionacrosseukaryotes
AT hunterbfraser comparativeexpressionprofilingrevealswidespreadcoordinatedevolutionofgeneexpressionacrosseukaryotes