Primary adenosquamous carcinoma of the liver: a case report

Adenosquamous carcinoma of the liver is a rare variant of cholangiocarcinoma. It is known to be a highly aggressive tumor with a poor prognosis, but its pathogenesis remains unclear owing to limited data in the literature. We report a case of 56-year-old woman who presented with a 1-week history of...

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Main Authors: Kyung Han Nam, Ji Yeon Kim
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2016-12-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2016-0077.pdf
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author Kyung Han Nam
Ji Yeon Kim
author_facet Kyung Han Nam
Ji Yeon Kim
author_sort Kyung Han Nam
collection DOAJ
description Adenosquamous carcinoma of the liver is a rare variant of cholangiocarcinoma. It is known to be a highly aggressive tumor with a poor prognosis, but its pathogenesis remains unclear owing to limited data in the literature. We report a case of 56-year-old woman who presented with a 1-week history of epigastric pain. Magnetic resonance imaging revealed a 6.5-cm ill-defined mass with low signal intensity in the left lobe of the liver, which was suspicious of cholangiocarcinoma. The patient underwent left hemihepatectomy. Microscopically, the tumor consisted of malignant glandular and squamous components and staged as pT2aN1. Despite postoperative chemoradiation, the patient had recurrence 8 months after surgery.
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spelling doaj.art-a4837b99f4dc4ed98cea3529396f65ea2022-12-22T01:46:02ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2016-12-0122450350810.3350/cmh.2016.00771332Primary adenosquamous carcinoma of the liver: a case reportKyung Han NamJi Yeon KimAdenosquamous carcinoma of the liver is a rare variant of cholangiocarcinoma. It is known to be a highly aggressive tumor with a poor prognosis, but its pathogenesis remains unclear owing to limited data in the literature. We report a case of 56-year-old woman who presented with a 1-week history of epigastric pain. Magnetic resonance imaging revealed a 6.5-cm ill-defined mass with low signal intensity in the left lobe of the liver, which was suspicious of cholangiocarcinoma. The patient underwent left hemihepatectomy. Microscopically, the tumor consisted of malignant glandular and squamous components and staged as pT2aN1. Despite postoperative chemoradiation, the patient had recurrence 8 months after surgery.http://e-cmh.org/upload/pdf/cmh-2016-0077.pdfAdenosquamous carcinomaLiverCholangiocarcinomaPathology
spellingShingle Kyung Han Nam
Ji Yeon Kim
Primary adenosquamous carcinoma of the liver: a case report
Clinical and Molecular Hepatology
Adenosquamous carcinoma
Liver
Cholangiocarcinoma
Pathology
title Primary adenosquamous carcinoma of the liver: a case report
title_full Primary adenosquamous carcinoma of the liver: a case report
title_fullStr Primary adenosquamous carcinoma of the liver: a case report
title_full_unstemmed Primary adenosquamous carcinoma of the liver: a case report
title_short Primary adenosquamous carcinoma of the liver: a case report
title_sort primary adenosquamous carcinoma of the liver a case report
topic Adenosquamous carcinoma
Liver
Cholangiocarcinoma
Pathology
url http://e-cmh.org/upload/pdf/cmh-2016-0077.pdf
work_keys_str_mv AT kyunghannam primaryadenosquamouscarcinomaoftheliveracasereport
AT jiyeonkim primaryadenosquamouscarcinomaoftheliveracasereport