Pili Torti: A Feature of Numerous Congenital and Acquired Conditions
Pili torti is a rare condition characterized by the presence of the hair shaft, which is flattened at irregular intervals and twisted 180° along its long axis. It is a form of hair shaft disorder with increased fragility. The condition is classified into inherited and acquired. Inherited forms may b...
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MDPI AG
2021-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/17/3901 |
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| author | Aleksandra Hoffmann Anna Waśkiel-Burnat Jakub Żółkiewicz Leszek Blicharz Adriana Rakowska Mohamad Goldust Małgorzata Olszewska Lidia Rudnicka |
| author_facet | Aleksandra Hoffmann Anna Waśkiel-Burnat Jakub Żółkiewicz Leszek Blicharz Adriana Rakowska Mohamad Goldust Małgorzata Olszewska Lidia Rudnicka |
| author_sort | Aleksandra Hoffmann |
| collection | DOAJ |
| description | Pili torti is a rare condition characterized by the presence of the hair shaft, which is flattened at irregular intervals and twisted 180° along its long axis. It is a form of hair shaft disorder with increased fragility. The condition is classified into inherited and acquired. Inherited forms may be either isolated or associated with numerous genetic diseases or syndromes (e.g., Menkes disease, Björnstad syndrome, Netherton syndrome, and Bazex-Dupré-Christol syndrome). Moreover, pili torti may be a feature of various ectodermal dysplasias (such as Rapp-Hodgkin syndrome and Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome). Acquired pili torti was described in numerous forms of alopecia (e.g., lichen planopilaris, discoid lupus erythematosus, dissecting cellulitis, folliculitis decalvans, alopecia areata) as well as neoplastic and systemic diseases (such as cutaneous T-cell lymphoma, scalp metastasis of breast cancer, anorexia nervosa, malnutrition, cataracts, and chronic graft-vs.-host disease). The condition may also be induced by several drugs (epidermal growth factor receptor inhibitors, oral retinoids, sodium valproate, and carbamide perhydrate). The diagnosis of pili torti is based on trichoscopic or microscopic examination. As pili torti is a marker of numerous congenital and acquired disorders, in every case, the search for the signs of underlying conditions is recommended. |
| first_indexed | 2024-03-10T08:09:00Z |
| format | Article |
| id | doaj.art-a484210bc7de4d118f2986421e826268 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T08:09:00Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a484210bc7de4d118f2986421e8262682023-11-22T10:49:06ZengMDPI AGJournal of Clinical Medicine2077-03832021-08-011017390110.3390/jcm10173901Pili Torti: A Feature of Numerous Congenital and Acquired ConditionsAleksandra Hoffmann0Anna Waśkiel-Burnat1Jakub Żółkiewicz2Leszek Blicharz3Adriana Rakowska4Mohamad Goldust5Małgorzata Olszewska6Lidia Rudnicka7Department of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, University Medical Center of the Johannes Gutenberg University, 55122 Mainz, GermanyDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82A, 02-008 Warsaw, PolandPili torti is a rare condition characterized by the presence of the hair shaft, which is flattened at irregular intervals and twisted 180° along its long axis. It is a form of hair shaft disorder with increased fragility. The condition is classified into inherited and acquired. Inherited forms may be either isolated or associated with numerous genetic diseases or syndromes (e.g., Menkes disease, Björnstad syndrome, Netherton syndrome, and Bazex-Dupré-Christol syndrome). Moreover, pili torti may be a feature of various ectodermal dysplasias (such as Rapp-Hodgkin syndrome and Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome). Acquired pili torti was described in numerous forms of alopecia (e.g., lichen planopilaris, discoid lupus erythematosus, dissecting cellulitis, folliculitis decalvans, alopecia areata) as well as neoplastic and systemic diseases (such as cutaneous T-cell lymphoma, scalp metastasis of breast cancer, anorexia nervosa, malnutrition, cataracts, and chronic graft-vs.-host disease). The condition may also be induced by several drugs (epidermal growth factor receptor inhibitors, oral retinoids, sodium valproate, and carbamide perhydrate). The diagnosis of pili torti is based on trichoscopic or microscopic examination. As pili torti is a marker of numerous congenital and acquired disorders, in every case, the search for the signs of underlying conditions is recommended.https://www.mdpi.com/2077-0383/10/17/3901pili tortitrichoscopyhair shaft abnormalitieshair shaft disorderhair diseasetwisted hair |
| spellingShingle | Aleksandra Hoffmann Anna Waśkiel-Burnat Jakub Żółkiewicz Leszek Blicharz Adriana Rakowska Mohamad Goldust Małgorzata Olszewska Lidia Rudnicka Pili Torti: A Feature of Numerous Congenital and Acquired Conditions Journal of Clinical Medicine pili torti trichoscopy hair shaft abnormalities hair shaft disorder hair disease twisted hair |
| title | Pili Torti: A Feature of Numerous Congenital and Acquired Conditions |
| title_full | Pili Torti: A Feature of Numerous Congenital and Acquired Conditions |
| title_fullStr | Pili Torti: A Feature of Numerous Congenital and Acquired Conditions |
| title_full_unstemmed | Pili Torti: A Feature of Numerous Congenital and Acquired Conditions |
| title_short | Pili Torti: A Feature of Numerous Congenital and Acquired Conditions |
| title_sort | pili torti a feature of numerous congenital and acquired conditions |
| topic | pili torti trichoscopy hair shaft abnormalities hair shaft disorder hair disease twisted hair |
| url | https://www.mdpi.com/2077-0383/10/17/3901 |
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