How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research

While confronted with the increasing complexity of the neurobiology of Parkinson’s disease (PD), we face the ever-increasing sloppiness of the conceptual definitions associated with poor methodological characterizations and the use of unacknowledged proxies, all of which are harmful contributors to...

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Main Author: Erwan Bezard
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/2/228
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author Erwan Bezard
author_facet Erwan Bezard
author_sort Erwan Bezard
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description While confronted with the increasing complexity of the neurobiology of Parkinson’s disease (PD), we face the ever-increasing sloppiness of the conceptual definitions associated with poor methodological characterizations and the use of unacknowledged proxies, all of which are harmful contributors to the overall slow progress of PD research. In this opinion paper, I share part of my frustration, acknowledge how I participate in this trend, and propose a simple remedy. Fighting against semantic or conceptual sloppiness is of paramount importance, notably for the benefit of newcomers to the field who otherwise would take for granted the classic assertions found <i>ad nauseam</i> in the literature.
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spelling doaj.art-a484a9c0e0dc4c38b2601d01a994baba2023-11-23T18:58:33ZengMDPI AGBiomolecules2218-273X2022-01-0112222810.3390/biom12020228How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy ResearchErwan Bezard0Institut des Maladies Neurodégénératives, UMR 5293, Université de Bordeaux, 33076 Bordeaux, FranceWhile confronted with the increasing complexity of the neurobiology of Parkinson’s disease (PD), we face the ever-increasing sloppiness of the conceptual definitions associated with poor methodological characterizations and the use of unacknowledged proxies, all of which are harmful contributors to the overall slow progress of PD research. In this opinion paper, I share part of my frustration, acknowledge how I participate in this trend, and propose a simple remedy. Fighting against semantic or conceptual sloppiness is of paramount importance, notably for the benefit of newcomers to the field who otherwise would take for granted the classic assertions found <i>ad nauseam</i> in the literature.https://www.mdpi.com/2218-273X/12/2/228Parkinson’s diseaseα-synucleinamyloidaggregation
spellingShingle Erwan Bezard
How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
Biomolecules
Parkinson’s disease
α-synuclein
amyloid
aggregation
title How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
title_full How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
title_fullStr How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
title_full_unstemmed How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
title_short How Lazy Reading and Semantic Sloppiness May Harm Progress in Synucleinopathy Research
title_sort how lazy reading and semantic sloppiness may harm progress in synucleinopathy research
topic Parkinson’s disease
α-synuclein
amyloid
aggregation
url https://www.mdpi.com/2218-273X/12/2/228
work_keys_str_mv AT erwanbezard howlazyreadingandsemanticsloppinessmayharmprogressinsynucleinopathyresearch