Exogenous NAD<sup>+</sup> Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway

Background: MUC2, a major component of the mucus layer in the intestine, is associated with antimicrobial activity and gut immune system function. Currently, mucin is mainly known for its critical function in defense against toxic molecules and pathogens. In this study, we investigated the stimulato...

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Bibliographic Details
Main Authors: Seongho Ma, Jiah Yeom, Young-Hee Lim
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/4/580