EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)

The current overview emphasizes on the physiological changes due to the combine effects of microgravity and ionizing radiation. Those two factors are significant to Astrobiology and our ambitions to travel into Space. The development of the technologies gives opportunity to combine and to make compa...

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Main Authors: Raina Ardasheva, Victor Yotov, Valentin Turiiski
Format: Article
Language:English
Published: Union of Scientists - Stara Zagora 2020-12-01
Series:Science & Research
Subjects:
Online Access: http://www.sandtr.org/download.php?id=94
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author Raina Ardasheva
Victor Yotov
Valentin Turiiski
author_facet Raina Ardasheva
Victor Yotov
Valentin Turiiski
author_sort Raina Ardasheva
collection DOAJ
description The current overview emphasizes on the physiological changes due to the combine effects of microgravity and ionizing radiation. Those two factors are significant to Astrobiology and our ambitions to travel into Space. The development of the technologies gives opportunity to combine and to make comparison between experiments carried out at real cosmic environment like the International space station (ISS) and ground ones, simulating the conditions of interstellar voyage. Experimental animals and cell cultures, representative for the specific system and organs, are used in those types of researches. Data obtained have traced many reliable findings: morphological and functional changes in neuronal tissues (expressed as decreased number of cells and change of their form), vascular system disorders (hemodynamics modulations, pulse rate and blood pressure alteration), and skeletal muscles weakness (change in volume and mass). Effects, due to ionizing radiation, are accelerating apoptosis and activating compensating mechanisms for oxidative stress. Both microgravity and irradiation by ionizing radiation are having combine effects in the cell cycles, genome mutations and apoptosis.
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spelling doaj.art-a486bdc930ab410288eb00d39b0cc63d2024-04-16T09:15:36ZengUnion of Scientists - Stara ZagoraScience & Research2535-07652020-12-0194EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)Raina ArdashevaVictor YotovValentin TuriiskiThe current overview emphasizes on the physiological changes due to the combine effects of microgravity and ionizing radiation. Those two factors are significant to Astrobiology and our ambitions to travel into Space. The development of the technologies gives opportunity to combine and to make comparison between experiments carried out at real cosmic environment like the International space station (ISS) and ground ones, simulating the conditions of interstellar voyage. Experimental animals and cell cultures, representative for the specific system and organs, are used in those types of researches. Data obtained have traced many reliable findings: morphological and functional changes in neuronal tissues (expressed as decreased number of cells and change of their form), vascular system disorders (hemodynamics modulations, pulse rate and blood pressure alteration), and skeletal muscles weakness (change in volume and mass). Effects, due to ionizing radiation, are accelerating apoptosis and activating compensating mechanisms for oxidative stress. Both microgravity and irradiation by ionizing radiation are having combine effects in the cell cycles, genome mutations and apoptosis. http://www.sandtr.org/download.php?id=94 microgravityweightlessnessionizing radiationrandom positioning machine (rpm)rat
spellingShingle Raina Ardasheva
Victor Yotov
Valentin Turiiski
EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
Science & Research
microgravity
weightlessness
ionizing radiation
random positioning machine (rpm)
rat
title EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
title_full EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
title_fullStr EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
title_full_unstemmed EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
title_short EFFECTS OF MICROGRAVITY AND IONIZING RADIATION OVER HUMAN BODY (A REVIEW)
title_sort effects of microgravity and ionizing radiation over human body a review
topic microgravity
weightlessness
ionizing radiation
random positioning machine (rpm)
rat
url http://www.sandtr.org/download.php?id=94
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AT victoryotov effectsofmicrogravityandionizingradiationoverhumanbodyareview
AT valentinturiiski effectsofmicrogravityandionizingradiationoverhumanbodyareview