Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses

Antibodies raised in Indian rhesus macaques (Macaca mulatta, MM) in many preclinical vaccine studies are often evaluated in vitro for titer, antigen-recognition breadth, neutralization potency, and/or effector function, and in vivo for potential associations with protection. However, despite relianc...

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Bibliographic Details
Main Authors: Austin W. Boesch, Nana Y Osei-Owusu, Andrew R Crowley, Thach H Chu, Ying N Chan, Joshua A Weiner, Pranay Bharadwaj, Rufus Hards, Mark E Adamo, Scott A Gerber, Sarah L Cocklin, Joern E Schmitz, Adam R Miles, Joshua W Eckman, Aaron J Belli, Keith A Reimann, Margaret E Ackerman
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
IgG
effector function
Fc receptor
nonhuman primate
Rhesus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00589/full

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