The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome
PURPOSEThis study aimed to evaluate the use of stone density variation coefficient (SDVC) as an indicator of stone heterogeneity and previously reported parameters for predicting extracorporeal shock wave lithotripsy (ESWL) outcome in urinary calculi. Moreover, a new formula that could be used to pr...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-05-01
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| Series: | Diagnostic and Interventional Radiology |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/the-usefulness-of-the-hounsfield-unit-and-stone-he/53685
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| _version_ | 1827823553872920576 |
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| author | Cemil Oktay Mahmut Çoraplı Ali Tutuş |
| author_facet | Cemil Oktay Mahmut Çoraplı Ali Tutuş |
| author_sort | Cemil Oktay |
| collection | DOAJ |
| description | PURPOSEThis study aimed to evaluate the use of stone density variation coefficient (SDVC) as an indicator of stone heterogeneity and previously reported parameters for predicting extracorporeal shock wave lithotripsy (ESWL) outcome in urinary calculi. Moreover, a new formula that could be used to predict ESWL success was suggested.METHODSA total of 850 patients, who underwent the first session of ESWL for urinary stones between 2015 and 2020, were examined, and 220 eligible patients were included in the study. Stone density variation coefficient and other parameters associated with stone attenuation values and stone size parameters were studied as potential predictors based on noncontrast com- puted tomography (NCCT). Extracorporeal shock wave lithotripsy success was considered after 3 months by radiography or NCCT. Logistic regression analysis was performed to determine the factors contributing to treatment success.RESULTSFor the 220 patients, ESWL success rate was 39.5%. The receiver operating characteristic analysis showed that SDVC (AUC=0.82; 95% confidence interval [CI]: 0.76–0.87; P < .001), mean stone density (AUC=0.81; 95% CI:0.75–0.87; P < .001), maximum stone density (AUC=0.70; 95% CI: 0.63–0.78; P < .001), stone volume (AUC=0.70; 95% CI: 0.62–0.77; P < .001), and major diam- eter (AUC=0.67; 95% CI: 0.59–0.74; P < .001) had significant prediction accuracy from high to low. Additionally, SDVC was found to be successful in predicting ESWL success, especially for patients with high mean stone density (OR = 10; 95% CI: 3.55–28.57; P < .001). The logistic regres- sion model, in which the “stone disintegration probability” (SDP) formula was found, correctly predicted ESWL success with a single session by 79.1%.CONCLUSIONIn conclusion, size and attenuation values were predictors of treatment success, and the best predictor was SDVC. Evaluation of SDP formula prior to ESWL could predict treatment outcomes and facilitate the decisions regarding treatment strategies. |
| first_indexed | 2024-03-12T02:13:23Z |
| format | Article |
| id | doaj.art-a48cb29ebfb6410585c24119d014267a |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:13:23Z |
| publishDate | 2022-05-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-a48cb29ebfb6410585c24119d014267a2023-09-06T12:09:08ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122022-05-0128318719210.5152/dir.2022.2094513049054The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcomeCemil Oktay0Mahmut Çoraplı1Ali Tutuş2 Department of Radiology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey Department of Radiology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey Department of Urology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey PURPOSEThis study aimed to evaluate the use of stone density variation coefficient (SDVC) as an indicator of stone heterogeneity and previously reported parameters for predicting extracorporeal shock wave lithotripsy (ESWL) outcome in urinary calculi. Moreover, a new formula that could be used to predict ESWL success was suggested.METHODSA total of 850 patients, who underwent the first session of ESWL for urinary stones between 2015 and 2020, were examined, and 220 eligible patients were included in the study. Stone density variation coefficient and other parameters associated with stone attenuation values and stone size parameters were studied as potential predictors based on noncontrast com- puted tomography (NCCT). Extracorporeal shock wave lithotripsy success was considered after 3 months by radiography or NCCT. Logistic regression analysis was performed to determine the factors contributing to treatment success.RESULTSFor the 220 patients, ESWL success rate was 39.5%. The receiver operating characteristic analysis showed that SDVC (AUC=0.82; 95% confidence interval [CI]: 0.76–0.87; P < .001), mean stone density (AUC=0.81; 95% CI:0.75–0.87; P < .001), maximum stone density (AUC=0.70; 95% CI: 0.63–0.78; P < .001), stone volume (AUC=0.70; 95% CI: 0.62–0.77; P < .001), and major diam- eter (AUC=0.67; 95% CI: 0.59–0.74; P < .001) had significant prediction accuracy from high to low. Additionally, SDVC was found to be successful in predicting ESWL success, especially for patients with high mean stone density (OR = 10; 95% CI: 3.55–28.57; P < .001). The logistic regres- sion model, in which the “stone disintegration probability” (SDP) formula was found, correctly predicted ESWL success with a single session by 79.1%.CONCLUSIONIn conclusion, size and attenuation values were predictors of treatment success, and the best predictor was SDVC. Evaluation of SDP formula prior to ESWL could predict treatment outcomes and facilitate the decisions regarding treatment strategies. http://www.dirjournal.org/archives/archive-detail/article-preview/the-usefulness-of-the-hounsfield-unit-and-stone-he/53685 |
| spellingShingle | Cemil Oktay Mahmut Çoraplı Ali Tutuş The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome Diagnostic and Interventional Radiology |
| title | The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| title_full | The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| title_fullStr | The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| title_full_unstemmed | The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| title_short | The usefulness of the Hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| title_sort | usefulness of the hounsfield unit and stone heterogeneity variation in predicting the shockwave lithotripsy outcome |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/the-usefulness-of-the-hounsfield-unit-and-stone-he/53685
|
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