Is Hypovitaminosis D a Risk Factor for Heart Failure?
Background: Several studies in recent years have shown the association between vitamin D levels and heart failure. Vitamin D deficiency is related to increased cardiovascular morbidity and mortality, with a higher risk of developing heart failure. In this systematic review, we aimed to assess recent...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/2/372 |
| _version_ | 1797619849237626880 |
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| author | Asmaa Carla Hagău Amalia Pușcaș Rodica Togănel Iolanda Muntean |
| author_facet | Asmaa Carla Hagău Amalia Pușcaș Rodica Togănel Iolanda Muntean |
| author_sort | Asmaa Carla Hagău |
| collection | DOAJ |
| description | Background: Several studies in recent years have shown the association between vitamin D levels and heart failure. Vitamin D deficiency is related to increased cardiovascular morbidity and mortality, with a higher risk of developing heart failure. In this systematic review, we aimed to assess recent studies that analyzed vitamin D deficiency and heart failure in adult and pediatric populations. (2) Methods: We conducted a systematic search for studies published in the following databases: PubMed and Scopus from January 2012 to October 2022. (3) Results: Most observational studies that were included found a significant association between hypovitaminosis D and heart failure. However, the beneficial role of vitamin D supplementation is still controversial due to the lack of randomized controlled trials. (4) Conclusions: Vitamin D may play an important role as a cardiovascular marker in heart failure patients. More well-designed studies are needed to investigate the relationship between vitamin D and heart failure and to determine if vitamin D supplementation could improve long-term outcomes. |
| first_indexed | 2024-03-11T08:32:41Z |
| format | Article |
| id | doaj.art-a49b6d7cb02344c5a8b59ae9e7aae7f7 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T08:32:41Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-a49b6d7cb02344c5a8b59ae9e7aae7f72023-11-16T21:40:22ZengMDPI AGLife2075-17292023-01-0113237210.3390/life13020372Is Hypovitaminosis D a Risk Factor for Heart Failure?Asmaa Carla Hagău0Amalia Pușcaș1Rodica Togănel2Iolanda Muntean3Doctoral School of Medicine and Pharmacy, I.O.S.U.D., George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Emergency Institute for Cardiovascular Diseases and Transplantation of Târgu Mureș, 540136 TarguMures, RomaniaDepartment of Biochemistry and Chemistry of Environmental Factors, Faculty of Pharmacy, University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Targu Mures, 540142 Targu Mures, RomaniaDepartment of Paediatrics, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, RomaniaClinic of Paediatric Cardiology, Emergency Institute for Cardiovascular Diseases and Transplantation of Târgu Mureș, University of Medicine, Pharmacy, Sciences and Technology “George Emil Palade” of Targu Mures, 540142 Târgu Mureș, RomaniaBackground: Several studies in recent years have shown the association between vitamin D levels and heart failure. Vitamin D deficiency is related to increased cardiovascular morbidity and mortality, with a higher risk of developing heart failure. In this systematic review, we aimed to assess recent studies that analyzed vitamin D deficiency and heart failure in adult and pediatric populations. (2) Methods: We conducted a systematic search for studies published in the following databases: PubMed and Scopus from January 2012 to October 2022. (3) Results: Most observational studies that were included found a significant association between hypovitaminosis D and heart failure. However, the beneficial role of vitamin D supplementation is still controversial due to the lack of randomized controlled trials. (4) Conclusions: Vitamin D may play an important role as a cardiovascular marker in heart failure patients. More well-designed studies are needed to investigate the relationship between vitamin D and heart failure and to determine if vitamin D supplementation could improve long-term outcomes.https://www.mdpi.com/2075-1729/13/2/372Vitamin D deficiencycardiovascularrisk factorsheart failureadultschildren |
| spellingShingle | Asmaa Carla Hagău Amalia Pușcaș Rodica Togănel Iolanda Muntean Is Hypovitaminosis D a Risk Factor for Heart Failure? Life Vitamin D deficiency cardiovascular risk factors heart failure adults children |
| title | Is Hypovitaminosis D a Risk Factor for Heart Failure? |
| title_full | Is Hypovitaminosis D a Risk Factor for Heart Failure? |
| title_fullStr | Is Hypovitaminosis D a Risk Factor for Heart Failure? |
| title_full_unstemmed | Is Hypovitaminosis D a Risk Factor for Heart Failure? |
| title_short | Is Hypovitaminosis D a Risk Factor for Heart Failure? |
| title_sort | is hypovitaminosis d a risk factor for heart failure |
| topic | Vitamin D deficiency cardiovascular risk factors heart failure adults children |
| url | https://www.mdpi.com/2075-1729/13/2/372 |
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