Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature
<p>Abstract</p> <p>Background</p> <p>Isolated angiitis of the central nervous system (IACNS) is a rare but severe vascular disease, which could present like an isolated inflammatory lesion on magnetic resonance imaging (MRI). To date, only a few such cases with tumor-li...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2011-08-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://www.wjso.com/content/9/1/97 |
| _version_ | 1811297326156742656 |
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| author | Li Guilin Li Shaowu Zhang Wei Yan Wei You Gan Jiang Tao |
| author_facet | Li Guilin Li Shaowu Zhang Wei Yan Wei You Gan Jiang Tao |
| author_sort | Li Guilin |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Isolated angiitis of the central nervous system (IACNS) is a rare but severe vascular disease, which could present like an isolated inflammatory lesion on magnetic resonance imaging (MRI). To date, only a few such cases with tumor-like IACNS have been reported.</p> <p>Case Presentation</p> <p>A 35-year-old woman presented with headache and left-sided weakness. MRI scans initially mislead us to a diagnosis of glioblastoma (GBM). Surgery was performed. The mass was sub-totally resected. Pathological examination confirmed a cerebral vasculitis. Radiological features, such as disproportionate mass effect, striped hemorrhage and abnormal enhancement of adjacent vessels, could be helpful to distinguish a tumor-like IACNS from a GBM. Single therapy with high doses of steroid did not improve the patient's condition. Combined therapy with prednisolone and cyclophosphamide showed great benefit to the patient. No relapse occurred during the period of 18 months follow-up.</p> <p>Conclusions</p> <p>Although a tumor-like IACNS has no established imaging features, a diagnosis of tumor-like IACNS should be suspected when MRI shows inappropriate presentations of a tumor. Greater awareness of this potential manifestation of IACNS may facilitate more prompt diagnosis and treatment.</p> |
| first_indexed | 2024-04-13T06:02:36Z |
| format | Article |
| id | doaj.art-a49bea15387c4bbda29ef200d62d24b8 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-13T06:02:36Z |
| publishDate | 2011-08-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-a49bea15387c4bbda29ef200d62d24b82022-12-22T02:59:24ZengBMCWorld Journal of Surgical Oncology1477-78192011-08-01919710.1186/1477-7819-9-97Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literatureLi GuilinLi ShaowuZhang WeiYan WeiYou GanJiang Tao<p>Abstract</p> <p>Background</p> <p>Isolated angiitis of the central nervous system (IACNS) is a rare but severe vascular disease, which could present like an isolated inflammatory lesion on magnetic resonance imaging (MRI). To date, only a few such cases with tumor-like IACNS have been reported.</p> <p>Case Presentation</p> <p>A 35-year-old woman presented with headache and left-sided weakness. MRI scans initially mislead us to a diagnosis of glioblastoma (GBM). Surgery was performed. The mass was sub-totally resected. Pathological examination confirmed a cerebral vasculitis. Radiological features, such as disproportionate mass effect, striped hemorrhage and abnormal enhancement of adjacent vessels, could be helpful to distinguish a tumor-like IACNS from a GBM. Single therapy with high doses of steroid did not improve the patient's condition. Combined therapy with prednisolone and cyclophosphamide showed great benefit to the patient. No relapse occurred during the period of 18 months follow-up.</p> <p>Conclusions</p> <p>Although a tumor-like IACNS has no established imaging features, a diagnosis of tumor-like IACNS should be suspected when MRI shows inappropriate presentations of a tumor. Greater awareness of this potential manifestation of IACNS may facilitate more prompt diagnosis and treatment.</p>http://www.wjso.com/content/9/1/97primary angiitisvasculitistumor-like lesionmimickingglioma |
| spellingShingle | Li Guilin Li Shaowu Zhang Wei Yan Wei You Gan Jiang Tao Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature World Journal of Surgical Oncology primary angiitis vasculitis tumor-like lesion mimicking glioma |
| title | Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature |
| title_full | Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature |
| title_fullStr | Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature |
| title_full_unstemmed | Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature |
| title_short | Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature |
| title_sort | isolated angiitis of the central nervous system with tumor like lesion mimicking brain malignant glioma a case report and review of the literature |
| topic | primary angiitis vasculitis tumor-like lesion mimicking glioma |
| url | http://www.wjso.com/content/9/1/97 |
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