Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019
Abstract Diabetes mellitus (DM) is currently one of the leading causes of mortality worldwide. However, the disease evolves differently across countries. This study intends to characterize the trends and assess the potential effects of marginalization on DM mortality between 1990 and 2019 in Mexico....
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-12831-z |
| _version_ | 1818553374529814528 |
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| author | Eduardo Gutiérrez-León Ricardo Antonio Escamilla-Santiago Pablo Martínez-Amezcua Usama Bilal Mariana Lazo Rafael Ogaz-González Malaquías López-Cervantes |
| author_facet | Eduardo Gutiérrez-León Ricardo Antonio Escamilla-Santiago Pablo Martínez-Amezcua Usama Bilal Mariana Lazo Rafael Ogaz-González Malaquías López-Cervantes |
| author_sort | Eduardo Gutiérrez-León |
| collection | DOAJ |
| description | Abstract Diabetes mellitus (DM) is currently one of the leading causes of mortality worldwide. However, the disease evolves differently across countries. This study intends to characterize the trends and assess the potential effects of marginalization on DM mortality between 1990 and 2019 in Mexico. We analyzed death certificates that listed DM as the underlying cause of death (N = 1,907,173), as well as the extent to which DM mortality changes were associated with marginalization through an age-period-cohort analysis. DM mortality increased in Mexico between 1990 and 2019; the change was faster in the first half and slowed down after 2004. The highest marginalization quintiles drove the changes in DM mortality trends during the study period, with a higher risk of dying in these quintiles as age increased. In recent cohorts, the highest marginalization quintiles doubled the risk of dying from DM as compared to the lowest. Renal complications was the main death driver among persons with DM, with a marked increase between 1999 and 2001. In conclusion, Mexico continues to have a substantially high DM mortality, but its pace slowed over time. Moreover, subnational differences in marginalization can partially explain such a trend. |
| first_indexed | 2024-12-12T09:25:01Z |
| format | Article |
| id | doaj.art-a49d654c57fe40df83a750c877494c39 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-12T09:25:01Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-a49d654c57fe40df83a750c877494c392022-12-22T00:29:03ZengNature PortfolioScientific Reports2045-23222022-06-011211910.1038/s41598-022-12831-zTrends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019Eduardo Gutiérrez-León0Ricardo Antonio Escamilla-Santiago1Pablo Martínez-Amezcua2Usama Bilal3Mariana Lazo4Rafael Ogaz-González5Malaquías López-Cervantes6Department of Public Health, School of Medicine, National Autonomous University of MexicoDepartment of Public Health, School of Medicine, National Autonomous University of MexicoDivision of General Medicine, Columbia University Irving Medical CenterUrban Health Collaborative, Drexel Dornsife School of Public HealthUrban Health Collaborative, Drexel Dornsife School of Public HealthDepartment of Public Health, School of Medicine, National Autonomous University of MexicoDepartment of Public Health, School of Medicine, National Autonomous University of MexicoAbstract Diabetes mellitus (DM) is currently one of the leading causes of mortality worldwide. However, the disease evolves differently across countries. This study intends to characterize the trends and assess the potential effects of marginalization on DM mortality between 1990 and 2019 in Mexico. We analyzed death certificates that listed DM as the underlying cause of death (N = 1,907,173), as well as the extent to which DM mortality changes were associated with marginalization through an age-period-cohort analysis. DM mortality increased in Mexico between 1990 and 2019; the change was faster in the first half and slowed down after 2004. The highest marginalization quintiles drove the changes in DM mortality trends during the study period, with a higher risk of dying in these quintiles as age increased. In recent cohorts, the highest marginalization quintiles doubled the risk of dying from DM as compared to the lowest. Renal complications was the main death driver among persons with DM, with a marked increase between 1999 and 2001. In conclusion, Mexico continues to have a substantially high DM mortality, but its pace slowed over time. Moreover, subnational differences in marginalization can partially explain such a trend.https://doi.org/10.1038/s41598-022-12831-z |
| spellingShingle | Eduardo Gutiérrez-León Ricardo Antonio Escamilla-Santiago Pablo Martínez-Amezcua Usama Bilal Mariana Lazo Rafael Ogaz-González Malaquías López-Cervantes Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 Scientific Reports |
| title | Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 |
| title_full | Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 |
| title_fullStr | Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 |
| title_full_unstemmed | Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 |
| title_short | Trends and effect of marginalization on diabetes mellitus-related mortality in Mexico from 1990 to 2019 |
| title_sort | trends and effect of marginalization on diabetes mellitus related mortality in mexico from 1990 to 2019 |
| url | https://doi.org/10.1038/s41598-022-12831-z |
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