Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer

Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer

Abstract Background Non-small cell lung cancer (NSCLC) is the leading cause of cancer morbidity and mortality worldwide. The prognosis of patients has been significantly improved by chemotherapy, but acquired drug resistance remains a major obstacle to NSCLC treatment. Circular RNAs (circRNAs), whic...

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Bibliographic Details
Main Authors: Xinyue Du, Weijie Luo, Hongwu Li, Qi Gu, Ping Huang, Cheng Wang, Na Li, Fanglan Liu, Chunhua Xia
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Cancer
Subjects:
CircRNAs
NSCLC
Gemcitabine resistance
MiR-582-5p
FGF9
WNT canonical and non-canonical signaling pathways
Online Access:https://doi.org/10.1186/s12943-025-02259-0

Internet

https://doi.org/10.1186/s12943-025-02259-0

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