Nanoparticles for antiparasitic drug delivery
As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body. In recent yea...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2019-01-01
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| Series: | Drug Delivery |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10717544.2019.1692968 |
| _version_ | 1818849251454615552 |
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| author | Yuzhu Sun Dongmei Chen Yuanhu Pan Wei Qu Haihong Hao Xu Wang Zhenli Liu Shuyu Xie |
| author_facet | Yuzhu Sun Dongmei Chen Yuanhu Pan Wei Qu Haihong Hao Xu Wang Zhenli Liu Shuyu Xie |
| author_sort | Yuzhu Sun |
| collection | DOAJ |
| description | As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body. In recent years, some kinds of ideal nanocarriers have been developed for antiparasitic drug delivery. In this review, the progress of the enhanced antiparasitic effects of different nanoparticles payload and their influencing factors were firstly summarized. Secondly, the transport and disposition process in the body were reviewed. Finally, the challenges and prospects of nanoparticles for antiparasitic drug delivery were proposed. This review will help scholars to understand the development trend of nanoparticles in the treatment of parasitic diseases and explore strategies in the development of more efficient nanocarriers to overcome the difficulty in the treatment of parasite infections in the future. |
| first_indexed | 2024-12-19T06:30:16Z |
| format | Article |
| id | doaj.art-a4a0588d3b26496b8c30618469eec73c |
| institution | Directory Open Access Journal |
| issn | 1071-7544 1521-0464 |
| language | English |
| last_indexed | 2024-12-19T06:30:16Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Drug Delivery |
| spelling | doaj.art-a4a0588d3b26496b8c30618469eec73c2022-12-21T20:32:26ZengTaylor & Francis GroupDrug Delivery1071-75441521-04642019-01-012611206122110.1080/10717544.2019.16929681692968Nanoparticles for antiparasitic drug deliveryYuzhu Sun0Dongmei Chen1Yuanhu Pan2Wei Qu3Haihong Hao4Xu Wang5Zhenli Liu6Shuyu Xie7National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesNational Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug ResiduesAs an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of antiparasitic drugs from the body. In recent years, some kinds of ideal nanocarriers have been developed for antiparasitic drug delivery. In this review, the progress of the enhanced antiparasitic effects of different nanoparticles payload and their influencing factors were firstly summarized. Secondly, the transport and disposition process in the body were reviewed. Finally, the challenges and prospects of nanoparticles for antiparasitic drug delivery were proposed. This review will help scholars to understand the development trend of nanoparticles in the treatment of parasitic diseases and explore strategies in the development of more efficient nanocarriers to overcome the difficulty in the treatment of parasite infections in the future.http://dx.doi.org/10.1080/10717544.2019.1692968nanoparticlesantiparasitic drugsbioavailabilitytransporttherapy effects |
| spellingShingle | Yuzhu Sun Dongmei Chen Yuanhu Pan Wei Qu Haihong Hao Xu Wang Zhenli Liu Shuyu Xie Nanoparticles for antiparasitic drug delivery Drug Delivery nanoparticles antiparasitic drugs bioavailability transport therapy effects |
| title | Nanoparticles for antiparasitic drug delivery |
| title_full | Nanoparticles for antiparasitic drug delivery |
| title_fullStr | Nanoparticles for antiparasitic drug delivery |
| title_full_unstemmed | Nanoparticles for antiparasitic drug delivery |
| title_short | Nanoparticles for antiparasitic drug delivery |
| title_sort | nanoparticles for antiparasitic drug delivery |
| topic | nanoparticles antiparasitic drugs bioavailability transport therapy effects |
| url | http://dx.doi.org/10.1080/10717544.2019.1692968 |
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