Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling

Mathematical models have been of great importance in various fields, especially for understanding the dynamical behaviour of biosystems. Several models, based on classical ordinary differential equations, delay differential equations, and stochastic processes are commonly employed to gain insights i...

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Main Authors: Oluwatosin Babasola, Evans Otieno Omondi, Kayode Oshinubi, Nancy Matendechere Imbusi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:AppliedMath
Subjects:
Online Access:https://www.mdpi.com/2673-9909/3/4/37
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author Oluwatosin Babasola
Evans Otieno Omondi
Kayode Oshinubi
Nancy Matendechere Imbusi
author_facet Oluwatosin Babasola
Evans Otieno Omondi
Kayode Oshinubi
Nancy Matendechere Imbusi
author_sort Oluwatosin Babasola
collection DOAJ
description Mathematical models have been of great importance in various fields, especially for understanding the dynamical behaviour of biosystems. Several models, based on classical ordinary differential equations, delay differential equations, and stochastic processes are commonly employed to gain insights into these systems. However, there is potential to extend such models further by combining the features from the classical approaches. This work investigates stochastic delay differential equations (SDDEs)-based models to understand the behaviour of biosystems. Numerical techniques for solving these models that demonstrate a more robust representation of real-life scenarios are presented. Additionally, quantitative roles of delay and noise to gain a deeper understanding of their influence on the system’s overall behaviour are analysed. Subsequently, numerical simulations that illustrate the model’s robustness are provided and the results suggest that SDDEs provide a more comprehensive representation of many biological systems, effectively accounting for the uncertainties that arise in real-life situations.
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spelling doaj.art-a4a1f0ca7dee48878a9d84496ff117ad2023-12-22T13:48:45ZengMDPI AGAppliedMath2673-99092023-10-013470272110.3390/appliedmath3040037Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease ModellingOluwatosin Babasola0Evans Otieno Omondi1Kayode Oshinubi2Nancy Matendechere Imbusi3Department of Mathematical Sciences, University of Bath, Bath BA2 7AY, UKInstitute of Mathematical Sciences, Strathmore University, Nairobi P.O. Box 59857-00200, KenyaSchool of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ 86011, USASchool of Mathematics and Actuarial Sciences, Technical University of Kenya, Nairobi P.O. Box 52428-00200, KenyaMathematical models have been of great importance in various fields, especially for understanding the dynamical behaviour of biosystems. Several models, based on classical ordinary differential equations, delay differential equations, and stochastic processes are commonly employed to gain insights into these systems. However, there is potential to extend such models further by combining the features from the classical approaches. This work investigates stochastic delay differential equations (SDDEs)-based models to understand the behaviour of biosystems. Numerical techniques for solving these models that demonstrate a more robust representation of real-life scenarios are presented. Additionally, quantitative roles of delay and noise to gain a deeper understanding of their influence on the system’s overall behaviour are analysed. Subsequently, numerical simulations that illustrate the model’s robustness are provided and the results suggest that SDDEs provide a more comprehensive representation of many biological systems, effectively accounting for the uncertainties that arise in real-life situations.https://www.mdpi.com/2673-9909/3/4/37stochastic delay differential equationbiosystemsdisease modellingEuler–MaruyamaMilsteinnumerical techniques and simulations
spellingShingle Oluwatosin Babasola
Evans Otieno Omondi
Kayode Oshinubi
Nancy Matendechere Imbusi
Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
AppliedMath
stochastic delay differential equation
biosystems
disease modelling
Euler–Maruyama
Milstein
numerical techniques and simulations
title Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
title_full Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
title_fullStr Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
title_full_unstemmed Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
title_short Stochastic Delay Differential Equations: A Comprehensive Approach for Understanding Biosystems with Application to Disease Modelling
title_sort stochastic delay differential equations a comprehensive approach for understanding biosystems with application to disease modelling
topic stochastic delay differential equation
biosystems
disease modelling
Euler–Maruyama
Milstein
numerical techniques and simulations
url https://www.mdpi.com/2673-9909/3/4/37
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