Single-nucleus and Spatially Resolved Intratumor Subtype Heterogeneity in Bladder Cancer

Single-nucleus and Spatially Resolved Intratumor Subtype Heterogeneity in Bladder Cancer

Background: Current bulk transcriptomic classification systems for bladder cancer do not consider the level of intratumor subtype heterogeneity. Objective: To investigate the extent and possible clinical impact of intratumor subtype heterogeneity across early and more advanced stages of bladder canc...

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Bibliographic Details
Main Authors:	Sia V. Lindskrog, Sofie S. Schmøkel, Iver Nordentoft, Philippe Lamy, Michael Knudsen, Frederik Prip, Trine Strandgaard, Jørgen Bjerggaard Jensen, Lars Dyrskjøt
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Series:	European Urology Open Science
Subjects:	Non–muscle-invasive bladder cancer Muscle-invasive bladder cancer Single-nucleus RNA sequencing Spatial transcriptomics Subtyping Intratumor heterogeneity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666168323001313

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