Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study
Purpose To compare the effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules (BTNs) among groups presenting with different nodule volumes. Materials and methods This retrospective study evaluated 186 patients with BTNs who underwent ultrasound guided RFA treatment. The BTNs were...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-01-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | http://dx.doi.org/10.1080/02656736.2020.1782485 |
| _version_ | 1818456725406089216 |
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| author | Wei-Che Lin Na-Ning Kan Hsiu-Ling Chen Sheng-Dean Luo Yu-Cheng Tung Wei-Chih Chen Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Yan-Ye Su Kai-Lun Cheng Jung Hwan Baek |
| author_facet | Wei-Che Lin Na-Ning Kan Hsiu-Ling Chen Sheng-Dean Luo Yu-Cheng Tung Wei-Chih Chen Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Yan-Ye Su Kai-Lun Cheng Jung Hwan Baek |
| author_sort | Wei-Che Lin |
| collection | DOAJ |
| description | Purpose To compare the effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules (BTNs) among groups presenting with different nodule volumes. Materials and methods This retrospective study evaluated 186 patients with BTNs who underwent ultrasound guided RFA treatment. The BTNs were categorized into small (≤10 ml); medium (10-30 ml); and large (>30 ml) according to the initial volume of BTNs before ablation. The RFA procedures were performed using the moving shot technique. The volume reduction ratio (VRR) of each nodule, cosmetic score, symptomatic score, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results At 1-month follow-up, the large nodules group showed significantly greater VRR compared to the other two groups (small, 31.88% ± 37.91; medium, 38.9% ± 19.18; large, 48.7% ± 20.43, p = .03). At 6-month follow-up, there was no significant difference of VRR among the three groups (small, 74.6% ± 20.92; medium, 68.1% ± 17.07; large, 75.0% ± 11.88). The most common presented complication was temporary vocal palsy (6 patients; small, n = 1; medium, n = 1; large, n = 3). Additionally, one skin burn, one hematoma, and one nodular rupture of BTNs occurred after the procedures. The complication rate of the large nodules group was highest among the three groups and showed a considerable difference (8 patients; small, n = 1, 2.1%; medium, n = 2, 4.5%; large, n = 5, 11.4%, p = .061). Conclusions RFA was confirmed as effective in patients with large thyroid nodule (>30ml), with therapeutic efficacy similar to patients with smaller thyroid nodules. |
| first_indexed | 2024-12-14T22:31:14Z |
| format | Article |
| id | doaj.art-a4a5f2c99269402aaa9d941798d9f22d |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-14T22:31:14Z |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-a4a5f2c99269402aaa9d941798d9f22d2022-12-21T22:45:15ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572020-01-013711082108910.1080/02656736.2020.17824851782485Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective studyWei-Che Lin0Na-Ning Kan1Hsiu-Ling Chen2Sheng-Dean Luo3Yu-Cheng Tung4Wei-Chih Chen5Chen-Kai Chou6Shun-Yu Chi7Meng-Hsiang Chen8Yan-Ye Su9Kai-Lun Cheng10Jung Hwan Baek11Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartments of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDepartment of Medical Imaging, Chung Shan Medical University HospitalDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical CenterPurpose To compare the effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules (BTNs) among groups presenting with different nodule volumes. Materials and methods This retrospective study evaluated 186 patients with BTNs who underwent ultrasound guided RFA treatment. The BTNs were categorized into small (≤10 ml); medium (10-30 ml); and large (>30 ml) according to the initial volume of BTNs before ablation. The RFA procedures were performed using the moving shot technique. The volume reduction ratio (VRR) of each nodule, cosmetic score, symptomatic score, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results At 1-month follow-up, the large nodules group showed significantly greater VRR compared to the other two groups (small, 31.88% ± 37.91; medium, 38.9% ± 19.18; large, 48.7% ± 20.43, p = .03). At 6-month follow-up, there was no significant difference of VRR among the three groups (small, 74.6% ± 20.92; medium, 68.1% ± 17.07; large, 75.0% ± 11.88). The most common presented complication was temporary vocal palsy (6 patients; small, n = 1; medium, n = 1; large, n = 3). Additionally, one skin burn, one hematoma, and one nodular rupture of BTNs occurred after the procedures. The complication rate of the large nodules group was highest among the three groups and showed a considerable difference (8 patients; small, n = 1, 2.1%; medium, n = 2, 4.5%; large, n = 5, 11.4%, p = .061). Conclusions RFA was confirmed as effective in patients with large thyroid nodule (>30ml), with therapeutic efficacy similar to patients with smaller thyroid nodules.http://dx.doi.org/10.1080/02656736.2020.1782485radiofrequency ablationthyroid nodulesnodule volumecomplicationnodular echogenicity |
| spellingShingle | Wei-Che Lin Na-Ning Kan Hsiu-Ling Chen Sheng-Dean Luo Yu-Cheng Tung Wei-Chih Chen Chen-Kai Chou Shun-Yu Chi Meng-Hsiang Chen Yan-Ye Su Kai-Lun Cheng Jung Hwan Baek Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study International Journal of Hyperthermia radiofrequency ablation thyroid nodules nodule volume complication nodular echogenicity |
| title | Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study |
| title_full | Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study |
| title_fullStr | Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study |
| title_full_unstemmed | Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study |
| title_short | Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study |
| title_sort | efficacy and safety of single session radiofrequency ablation for benign thyroid nodules of different sizes a retrospective study |
| topic | radiofrequency ablation thyroid nodules nodule volume complication nodular echogenicity |
| url | http://dx.doi.org/10.1080/02656736.2020.1782485 |
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