Resting-state functional magnetic resonance imaging of the subthalamic microlesion and stimulation effects in Parkinson's disease: Indications of a principal role of the brainstem

Resting-state functional magnetic resonance imaging of the subthalamic microlesion and stimulation effects in Parkinson's disease: Indications of a principal role of the brainstem

During implantation of deep-brain stimulation (DBS) electrodes in the target structure, neurosurgeons and neurologists commonly observe a “microlesion effect” (MLE), which occurs well before initiating subthalamic DBS. This phenomenon typically leads to a transitory improvement of motor symptoms of...

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Bibliographic Details
Main Authors: Štefan Holiga, Karsten Mueller, Harald E. Möller, Dušan Urgošík, Evžen Růžička, Matthias L. Schroeter, Robert Jech
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:NeuroImage: Clinical
Subjects:
Parkinson's disease
Microlesion effect
Brainstem
Resting-state fMRI
Deep-brain stimulation
Subthalamic nucleus
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215001461

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