Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease
Introduction: Children account for a relatively small proportion of laboratory-confirmed SARS-CoV-2 infections. In children, COVID-19 usually has a relatively mild course. However, in rare cases, severe disorders can be observed, and clinical manifestations may differ from adults. Purpose: The aim o...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Journal of Infection and Public Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034120307851 |
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| author | Anna Mania Katarzyna Mazur-Melewska Karol Lubarski Jadwiga Kuczma-Napierała Justyna Mazurek Katarzyna Jończyk-Potoczna Wojciech Służewski Magdalena Figlerowicz |
| author_facet | Anna Mania Katarzyna Mazur-Melewska Karol Lubarski Jadwiga Kuczma-Napierała Justyna Mazurek Katarzyna Jończyk-Potoczna Wojciech Służewski Magdalena Figlerowicz |
| author_sort | Anna Mania |
| collection | DOAJ |
| description | Introduction: Children account for a relatively small proportion of laboratory-confirmed SARS-CoV-2 infections. In children, COVID-19 usually has a relatively mild course. However, in rare cases, severe disorders can be observed, and clinical manifestations may differ from adults. Purpose: The aim of this study is to analyse the frequency, clinical picture and outcome of COVID-19 in children based on the experience from the tertiary care centre and regional sanitary-epidemiological office. Methods: We report a study regarding 106 cases of confirmed SARS-CoV-2 infection cases in PCR from a nasopharyngeal swab (age range 1-month – 17-years). In all cases, history was taken. In children who required hospital admission, physical examination and laboratory test were performed according to clinical indications. Results: Twelve of the patients required admission to the hospital. The most common symptoms were anosmia and dysgeusia (75%) and headaches (49%) in outpatients and fever in hospitalised children (75%). Three children from the hospitalised group developed a severe course with increased inflammatory indexes. The clinical picture was more severe in younger children from the hospitalised group. Treatment options were regarded individually in all cases. Conclusion: Our study is the first tour knowledge regarding the clinical course of COVID-19 in Polish children. In general, the clinical course of COVID-19 was mild with anosmia and dysgeusia as the most common symptoms. However, in hospitalised children, a severe progression of the disease and less typical signs as aplastic anaemia may be developed. |
| first_indexed | 2024-12-17T20:49:35Z |
| format | Article |
| id | doaj.art-a4ae140bc2164cb398206ce7cd50044b |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-17T20:49:35Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-a4ae140bc2164cb398206ce7cd50044b2022-12-21T21:33:04ZengElsevierJournal of Infection and Public Health1876-03412021-03-01143374379Wide spectrum of clinical picture of COVID-19 in children — From mild to severe diseaseAnna Mania0Katarzyna Mazur-Melewska1Karol Lubarski2Jadwiga Kuczma-Napierała3Justyna Mazurek4Katarzyna Jończyk-Potoczna5Wojciech Służewski6Magdalena Figlerowicz7Department of Infectious Diseases and Child Neurology, University of Medical Sciences in Poznań, Poland; Corresponding author at: Department of Infectious Diseases and Child Neurology, University of Medical Sciences, ul. Szpitalna 27/33, 60-572 Poznan, Poland.Department of Infectious Diseases and Child Neurology, University of Medical Sciences in Poznań, PolandDepartment of Infectious Diseases and Child Neurology, University of Medical Sciences in Poznań, PolandRegional Sanitary-Epidemiological Station in Poznan (WSSE), PolandRegional Sanitary-Epidemiological Station in Poznan (WSSE), PolandDepartment of Pediatric Radiology, University of Medical Sciences Poznan, PolandDepartment of Infectious Diseases and Child Neurology, University of Medical Sciences in Poznań, PolandDepartment of Infectious Diseases and Child Neurology, University of Medical Sciences in Poznań, PolandIntroduction: Children account for a relatively small proportion of laboratory-confirmed SARS-CoV-2 infections. In children, COVID-19 usually has a relatively mild course. However, in rare cases, severe disorders can be observed, and clinical manifestations may differ from adults. Purpose: The aim of this study is to analyse the frequency, clinical picture and outcome of COVID-19 in children based on the experience from the tertiary care centre and regional sanitary-epidemiological office. Methods: We report a study regarding 106 cases of confirmed SARS-CoV-2 infection cases in PCR from a nasopharyngeal swab (age range 1-month – 17-years). In all cases, history was taken. In children who required hospital admission, physical examination and laboratory test were performed according to clinical indications. Results: Twelve of the patients required admission to the hospital. The most common symptoms were anosmia and dysgeusia (75%) and headaches (49%) in outpatients and fever in hospitalised children (75%). Three children from the hospitalised group developed a severe course with increased inflammatory indexes. The clinical picture was more severe in younger children from the hospitalised group. Treatment options were regarded individually in all cases. Conclusion: Our study is the first tour knowledge regarding the clinical course of COVID-19 in Polish children. In general, the clinical course of COVID-19 was mild with anosmia and dysgeusia as the most common symptoms. However, in hospitalised children, a severe progression of the disease and less typical signs as aplastic anaemia may be developed.http://www.sciencedirect.com/science/article/pii/S1876034120307851COVID-19ChildrenClinical courseAnosmiaDysgeusiaAplastic anaemia |
| spellingShingle | Anna Mania Katarzyna Mazur-Melewska Karol Lubarski Jadwiga Kuczma-Napierała Justyna Mazurek Katarzyna Jończyk-Potoczna Wojciech Służewski Magdalena Figlerowicz Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease Journal of Infection and Public Health COVID-19 Children Clinical course Anosmia Dysgeusia Aplastic anaemia |
| title | Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease |
| title_full | Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease |
| title_fullStr | Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease |
| title_full_unstemmed | Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease |
| title_short | Wide spectrum of clinical picture of COVID-19 in children — From mild to severe disease |
| title_sort | wide spectrum of clinical picture of covid 19 in children from mild to severe disease |
| topic | COVID-19 Children Clinical course Anosmia Dysgeusia Aplastic anaemia |
| url | http://www.sciencedirect.com/science/article/pii/S1876034120307851 |
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