Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia

Gastrointestinal (GI) angiodysplasia is a rare cause of lower GI bleeding in the paediatric population. This disease caused intermittent per-rectal bleeding and severe anemia in 2-year-old girl with Turner's syndrome. She was initially suspected to have Meckel's diverticulum and taken to t...

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Main Authors: Ryo Tamura, Corina Moldovan, Milan Gopal
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pediatric Surgery Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213576620301366
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author Ryo Tamura
Corina Moldovan
Milan Gopal
author_facet Ryo Tamura
Corina Moldovan
Milan Gopal
author_sort Ryo Tamura
collection DOAJ
description Gastrointestinal (GI) angiodysplasia is a rare cause of lower GI bleeding in the paediatric population. This disease caused intermittent per-rectal bleeding and severe anemia in 2-year-old girl with Turner's syndrome. She was initially suspected to have Meckel's diverticulum and taken to the operation room for laparoscopy. A Meckel's diverticula was not found but an extensive distribution of abnormal vessels on the surface of the small bowel was noted from close to the duodeno-jejunal junction to the terminal ileum. GI angiodysplasia was suspected but the lesion was too extensive to be resected. It was also not clear if any specific area was the source of the current bleeding. After conversion to open surgery, an enterotomy was done in the mid portion of the affected bowel and an on table enteroscopy was done. This revealed a normal mucosal lining in the visualized areas and so was not contributory. Prior to closure of the enterotomy a doughnut of bowel was taken for histopathology. This confirmed small bowel angiodysplasia. She had one minor recurrence of lower GI bleeding 4 months later but has been well since then. This case sheds light on angiodysplasia as a cause of lower GI bleeding and we discuss its diagnostic and management options.
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spelling doaj.art-a4ae96a65b9a4eab9349de247abcab422022-12-21T23:39:19ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662020-08-0159101502Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasiaRyo Tamura0Corina Moldovan1Milan Gopal2Department of Paediatric Surgery, Great North Children's Hospital, Royal Victoria Infirmary (RVI), Queens Victoria Rd, Newcastle upon Tyne, England, NE1 4LP, UK; Corresponding author.Cellular Pathology, Great North Children's Hospital, RVI, UKDepartment of Paediatric Surgery, Great North Children's Hospital, Royal Victoria Infirmary (RVI), Queens Victoria Rd, Newcastle upon Tyne, England, NE1 4LP, UKGastrointestinal (GI) angiodysplasia is a rare cause of lower GI bleeding in the paediatric population. This disease caused intermittent per-rectal bleeding and severe anemia in 2-year-old girl with Turner's syndrome. She was initially suspected to have Meckel's diverticulum and taken to the operation room for laparoscopy. A Meckel's diverticula was not found but an extensive distribution of abnormal vessels on the surface of the small bowel was noted from close to the duodeno-jejunal junction to the terminal ileum. GI angiodysplasia was suspected but the lesion was too extensive to be resected. It was also not clear if any specific area was the source of the current bleeding. After conversion to open surgery, an enterotomy was done in the mid portion of the affected bowel and an on table enteroscopy was done. This revealed a normal mucosal lining in the visualized areas and so was not contributory. Prior to closure of the enterotomy a doughnut of bowel was taken for histopathology. This confirmed small bowel angiodysplasia. She had one minor recurrence of lower GI bleeding 4 months later but has been well since then. This case sheds light on angiodysplasia as a cause of lower GI bleeding and we discuss its diagnostic and management options.http://www.sciencedirect.com/science/article/pii/S2213576620301366Gastrointestinal bleedingAngiodysplasiaSmall bowel bleeding
spellingShingle Ryo Tamura
Corina Moldovan
Milan Gopal
Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
Journal of Pediatric Surgery Case Reports
Gastrointestinal bleeding
Angiodysplasia
Small bowel bleeding
title Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
title_full Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
title_fullStr Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
title_full_unstemmed Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
title_short Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
title_sort tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
topic Gastrointestinal bleeding
Angiodysplasia
Small bowel bleeding
url http://www.sciencedirect.com/science/article/pii/S2213576620301366
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AT corinamoldovan tranexamicacidforbleedinginachildwithextensivesmallbowelangiodysplasia
AT milangopal tranexamicacidforbleedinginachildwithextensivesmallbowelangiodysplasia