Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-<i>N</i>1-inosine 5′-monophosphate, Analogues and Early Structure-Activity Relationship
Although a monoclonal antibody targeting the multifunctional ectoenzyme CD38 is an FDA-approved drug, few small molecule inhibitors exist for this enzyme that catalyzes inter alia the formation and metabolism of the <i>N</i>1-ribosylated, Ca<sup>2+</sup>-mobilizing, second me...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/23/7165 |