Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction
Background and study aims The clinical outcome of the new hybrid drainage method for unresectable malignant hilar biliary obstruction (UMHBO) has not yet been compared with that of the partial stent-in-stent (PSIS) method with three or more stents. Patients and methods Patients with UMHBO...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2023-03-01
|
| Series: | Endoscopy International Open |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-2039-3936 |
| _version_ | 1827980958163271680 |
|---|---|
| author | Motohiro Yoshinari Susumu Hijioka Yoshikuni Nagashio Yuta Maruki Akihiro Ohba Yuki Kawasaki Kotaro Takeshita Chigusa Morizane Yasuhito Tanaka Takuji Okusaka |
| author_facet | Motohiro Yoshinari Susumu Hijioka Yoshikuni Nagashio Yuta Maruki Akihiro Ohba Yuki Kawasaki Kotaro Takeshita Chigusa Morizane Yasuhito Tanaka Takuji Okusaka |
| author_sort | Motohiro Yoshinari |
| collection | DOAJ |
| description | Background and study aims The clinical outcome of the new hybrid drainage method for unresectable malignant hilar biliary obstruction (UMHBO) has not yet been compared with that of the partial stent-in-stent (PSIS) method with three or more stents.
Patients and methods Patients with UMHBO underwent drainage of three segments using the hybrid or PSIS method. The clinical outcomes of both methods were compared retrospectively.
Results Overall, 54 patients underwent the hybrid (n = 31) or PSIS (n = 23) method of drainage with three or more stents for UMHBO. There were no significant differences in the technical success rate (hybrid vs. PSIS, 87.1 % vs. 87 %), clinical success rate according to per-protocol analysis (81.5 % vs. 70 %), early adverse events rate (14.8 % vs. 10%), late adverse events rate (7.4 % vs. 0 %), and technical success rate of the endoscopic transpapillary reintervention (90.9 % vs. 100 %). Time to recurrent biliary obstruction (TRBO) of the hybrid and PSIS methods was 178 and 231 days, respectively, with no significant difference (P = 0.354).
Conclusions The choice between the two methods should be made at the physician’s discretion. |
| first_indexed | 2024-04-09T22:01:13Z |
| format | Article |
| id | doaj.art-a4b50de606be464d94a0af3b2fa086d0 |
| institution | Directory Open Access Journal |
| issn | 2364-3722 2196-9736 |
| language | English |
| last_indexed | 2024-04-09T22:01:13Z |
| publishDate | 2023-03-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Endoscopy International Open |
| spelling | doaj.art-a4b50de606be464d94a0af3b2fa086d02023-03-24T00:03:56ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362023-03-011103E276E28310.1055/a-2039-3936Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstructionMotohiro Yoshinari0Susumu Hijioka1Yoshikuni Nagashio2Yuta Maruki3Akihiro Ohba4Yuki Kawasaki5Kotaro Takeshita6Chigusa Morizane7Yasuhito Tanaka8Takuji Okusaka9National Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanKumamoto University, Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto, JapanNational Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, JapanBackground and study aims The clinical outcome of the new hybrid drainage method for unresectable malignant hilar biliary obstruction (UMHBO) has not yet been compared with that of the partial stent-in-stent (PSIS) method with three or more stents. Patients and methods Patients with UMHBO underwent drainage of three segments using the hybrid or PSIS method. The clinical outcomes of both methods were compared retrospectively. Results Overall, 54 patients underwent the hybrid (n = 31) or PSIS (n = 23) method of drainage with three or more stents for UMHBO. There were no significant differences in the technical success rate (hybrid vs. PSIS, 87.1 % vs. 87 %), clinical success rate according to per-protocol analysis (81.5 % vs. 70 %), early adverse events rate (14.8 % vs. 10%), late adverse events rate (7.4 % vs. 0 %), and technical success rate of the endoscopic transpapillary reintervention (90.9 % vs. 100 %). Time to recurrent biliary obstruction (TRBO) of the hybrid and PSIS methods was 178 and 231 days, respectively, with no significant difference (P = 0.354). Conclusions The choice between the two methods should be made at the physician’s discretion.http://www.thieme-connect.de/DOI/DOI?10.1055/a-2039-3936 |
| spellingShingle | Motohiro Yoshinari Susumu Hijioka Yoshikuni Nagashio Yuta Maruki Akihiro Ohba Yuki Kawasaki Kotaro Takeshita Chigusa Morizane Yasuhito Tanaka Takuji Okusaka Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction Endoscopy International Open |
| title | Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction |
| title_full | Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction |
| title_fullStr | Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction |
| title_full_unstemmed | Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction |
| title_short | Comparison of the hybrid and partial stent-in-stent method for endoscopic three-segment drainage for unresectable malignant hilar biliary obstruction |
| title_sort | comparison of the hybrid and partial stent in stent method for endoscopic three segment drainage for unresectable malignant hilar biliary obstruction |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/a-2039-3936 |
| work_keys_str_mv | AT motohiroyoshinari comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT susumuhijioka comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT yoshikuninagashio comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT yutamaruki comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT akihiroohba comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT yukikawasaki comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT kotarotakeshita comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT chigusamorizane comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT yasuhitotanaka comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction AT takujiokusaka comparisonofthehybridandpartialstentinstentmethodforendoscopicthreesegmentdrainageforunresectablemalignanthilarbiliaryobstruction |