The Clinical Profile of Patients with COPD Is Conditioned by Age

In recent years, many studies have analyzed the importance of integrating time, or aging, into the equation that relates genetics and the environment to the development and origin of COPD. Under conditions of daily clinical practice, our study attempts to identify the differences in the clinical pro...

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Main Authors: Diego Morena, José Luis Izquierdo, Juan Rodríguez, Jesús Cuesta, María Benavent, Alejandro Perralejo, José Miguel Rodríguez
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/24/7595
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author Diego Morena
José Luis Izquierdo
Juan Rodríguez
Jesús Cuesta
María Benavent
Alejandro Perralejo
José Miguel Rodríguez
author_facet Diego Morena
José Luis Izquierdo
Juan Rodríguez
Jesús Cuesta
María Benavent
Alejandro Perralejo
José Miguel Rodríguez
author_sort Diego Morena
collection DOAJ
description In recent years, many studies have analyzed the importance of integrating time, or aging, into the equation that relates genetics and the environment to the development and origin of COPD. Under conditions of daily clinical practice, our study attempts to identify the differences in the clinical profile of patients with COPD according to age and the impact on the global burden of the disease. This study is non-interventional and observational, using artificial intelligence and data captured from electronic medical records. The study population included patients who were diagnosed with COPD between 2011 and 2021. A total of 73,901 patients had a diagnosis of COPD. The mean age was 73 years (95% CI: 72.9–73.1), and 56,763 were men (76.8%). We observed a specific prevalence of obesity, heart failure, depression, and hiatal hernia in women (<i>p</i> < 0.001), and ischemic heart disease and obstructive sleep apnea (OSA) in men (<i>p</i> < 0.001). In the analysis by age ranges, a progressive increase in cardiovascular risk factors was observed with age. In conclusion, in a real-life setting, COPD is a disease that primarily affects older subjects and frequently presents with comorbidities that are decisive in the evolutionary course of the disease.
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spelling doaj.art-a4be1a29644548cfbce3e2e1931ac2ad2023-12-22T14:17:06ZengMDPI AGJournal of Clinical Medicine2077-03832023-12-011224759510.3390/jcm12247595The Clinical Profile of Patients with COPD Is Conditioned by AgeDiego Morena0José Luis Izquierdo1Juan Rodríguez2Jesús Cuesta3María Benavent4Alejandro Perralejo5José Miguel Rodríguez6Pulmonology Department, Respiratory Medicine, Hospital Universitario de Guadalajara, 19002 Guadalajara, SpainPulmonology Department, Respiratory Medicine, Hospital Universitario de Guadalajara, 19002 Guadalajara, SpainGeriatric Medicine, Hospital Universitario de Guadalajara, 19002 Guadalajara, SpainDepartment of Medicine and Medical Specialties, University of Alcalá, 28871 Alcalá de Henares, SpainSAVANA, 28013 Madrid, SpainSAVANA, 28013 Madrid, SpainDepartment of Medicine and Medical Specialties, University of Alcalá, 28871 Alcalá de Henares, SpainIn recent years, many studies have analyzed the importance of integrating time, or aging, into the equation that relates genetics and the environment to the development and origin of COPD. Under conditions of daily clinical practice, our study attempts to identify the differences in the clinical profile of patients with COPD according to age and the impact on the global burden of the disease. This study is non-interventional and observational, using artificial intelligence and data captured from electronic medical records. The study population included patients who were diagnosed with COPD between 2011 and 2021. A total of 73,901 patients had a diagnosis of COPD. The mean age was 73 years (95% CI: 72.9–73.1), and 56,763 were men (76.8%). We observed a specific prevalence of obesity, heart failure, depression, and hiatal hernia in women (<i>p</i> < 0.001), and ischemic heart disease and obstructive sleep apnea (OSA) in men (<i>p</i> < 0.001). In the analysis by age ranges, a progressive increase in cardiovascular risk factors was observed with age. In conclusion, in a real-life setting, COPD is a disease that primarily affects older subjects and frequently presents with comorbidities that are decisive in the evolutionary course of the disease.https://www.mdpi.com/2077-0383/12/24/7595COPDbig dataartificial intelligenceagecomorbiditiesdaily clinical practice
spellingShingle Diego Morena
José Luis Izquierdo
Juan Rodríguez
Jesús Cuesta
María Benavent
Alejandro Perralejo
José Miguel Rodríguez
The Clinical Profile of Patients with COPD Is Conditioned by Age
Journal of Clinical Medicine
COPD
big data
artificial intelligence
age
comorbidities
daily clinical practice
title The Clinical Profile of Patients with COPD Is Conditioned by Age
title_full The Clinical Profile of Patients with COPD Is Conditioned by Age
title_fullStr The Clinical Profile of Patients with COPD Is Conditioned by Age
title_full_unstemmed The Clinical Profile of Patients with COPD Is Conditioned by Age
title_short The Clinical Profile of Patients with COPD Is Conditioned by Age
title_sort clinical profile of patients with copd is conditioned by age
topic COPD
big data
artificial intelligence
age
comorbidities
daily clinical practice
url https://www.mdpi.com/2077-0383/12/24/7595
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