Graph reasoning method enhanced by relational transformers and knowledge distillation for drug-related side effect prediction

Summary: Identifying the side effects related to drugs is beneficial for reducing the risk of drug development failure and saving the drug development cost. We proposed a graph reasoning method, RKDSP, to fuse the semantics of multiple connection relationships, the local knowledge within each meta-p...

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Bibliographic Details
Main Authors: Honglei Bai, Siyuan Lu, Tiangang Zhang, Hui Cui, Toshiya Nakaguchi, Ping Xuan
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007934