Biocompatibility Issue Of Tissue Engineered Heart Valves
Tissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue. It is expected that it will be characterized by high durability, which is very impo...
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| Format: | Article |
| Language: | English |
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Polish Academy of Sciences
2015-09-01
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| Series: | Archives of Metallurgy and Materials |
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| Online Access: | http://www.degruyter.com/view/j/amm.2015.60.issue-3/amm-2015-0372/amm-2015-0372.xml?format=INT |
| _version_ | 1811293038250557440 |
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| author | Wilczek P. |
| author_facet | Wilczek P. |
| author_sort | Wilczek P. |
| collection | DOAJ |
| description | Tissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue. It is expected that it will be characterized by high durability, which is very important from the social and clinical point of view. The aim of the study was to compare the cytotoxic effect of enzymatic and detergent acellularization methods commonly used for the biological scaffold preparation. It seems that the use of enzymatic methods, allows efficient donor cells removal while maintaining the ability to autologous cell seeding. Heart valves bioprosthesis created using these techniques, may be a good alternative to the currently used prostheses. |
| first_indexed | 2024-04-13T04:54:37Z |
| format | Article |
| id | doaj.art-a4c32de7151c44a79b7b14686233f748 |
| institution | Directory Open Access Journal |
| issn | 2300-1909 |
| language | English |
| last_indexed | 2024-04-13T04:54:37Z |
| publishDate | 2015-09-01 |
| publisher | Polish Academy of Sciences |
| record_format | Article |
| series | Archives of Metallurgy and Materials |
| spelling | doaj.art-a4c32de7151c44a79b7b14686233f7482022-12-22T03:01:32ZengPolish Academy of SciencesArchives of Metallurgy and Materials2300-19092015-09-016032261226610.1515/amm-2015-0372amm-2015-0372Biocompatibility Issue Of Tissue Engineered Heart ValvesWilczek P.0 HEART PROSTHESIS INSTITUTE, BIOENGINEERING LABORATORY, 345A WOLNOSCI STR., ZABRZE 41-800 POLANDTissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue. It is expected that it will be characterized by high durability, which is very important from the social and clinical point of view. The aim of the study was to compare the cytotoxic effect of enzymatic and detergent acellularization methods commonly used for the biological scaffold preparation. It seems that the use of enzymatic methods, allows efficient donor cells removal while maintaining the ability to autologous cell seeding. Heart valves bioprosthesis created using these techniques, may be a good alternative to the currently used prostheses.http://www.degruyter.com/view/j/amm.2015.60.issue-3/amm-2015-0372/amm-2015-0372.xml?format=INTtissue engineeringheart valvecytotoxicityscaffold |
| spellingShingle | Wilczek P. Biocompatibility Issue Of Tissue Engineered Heart Valves Archives of Metallurgy and Materials tissue engineering heart valve cytotoxicity scaffold |
| title | Biocompatibility Issue Of Tissue Engineered Heart Valves |
| title_full | Biocompatibility Issue Of Tissue Engineered Heart Valves |
| title_fullStr | Biocompatibility Issue Of Tissue Engineered Heart Valves |
| title_full_unstemmed | Biocompatibility Issue Of Tissue Engineered Heart Valves |
| title_short | Biocompatibility Issue Of Tissue Engineered Heart Valves |
| title_sort | biocompatibility issue of tissue engineered heart valves |
| topic | tissue engineering heart valve cytotoxicity scaffold |
| url | http://www.degruyter.com/view/j/amm.2015.60.issue-3/amm-2015-0372/amm-2015-0372.xml?format=INT |
| work_keys_str_mv | AT wilczekp biocompatibilityissueoftissueengineeredheartvalves |