Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors
Experiments were focused on the prevention of diarrhoea in weaned piglets by means of enterotoxigenic strains of Escherichia coli (ETEC) with colonizing factors K88 (F4). The process of immunization consisted of intramuscular administration of ETEC strain bacterin one day prior to weaning and oral a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Czech Academy of Agricultural Sciences
2005-07-01
|
| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-200507-0005_oral-immunization-against-enterotoxigenic-colibacillosis-in-weaned-piglets-by-non-pathogenic-escherichia-colist.php |
| _version_ | 1828006875220672512 |
|---|---|
| author | P. Alexa J. Hamrik K. Stouracova E. Salajka |
| author_facet | P. Alexa J. Hamrik K. Stouracova E. Salajka |
| author_sort | P. Alexa |
| collection | DOAJ |
| description | Experiments were focused on the prevention of diarrhoea in weaned piglets by means of enterotoxigenic strains of Escherichia coli (ETEC) with colonizing factors K88 (F4). The process of immunization consisted of intramuscular administration of ETEC strain bacterin one day prior to weaning and oral administration of a live culture of non-pathogenic E. coli strain containing colonizing factors (O149:K88; STa-, LT-) in 3 hours after weaning. The shedding of the K88 positive E. coli strains was monitored for 3 weeks after weaning by the culture of rectal swabs. The efficacy of such immunization protocol was tested by challenge exposure to enterotoxigenic E. coli O149:K88, LT+ strain on the third or the tenth day after weaning. Following the oral administration of non-pathogenic E. coli strain containing colonizing factors K88 to piglets, the shedding of the administered strain continued for 9 days. No or very small protection against diarrhoea following the challenge exposure to enterotoxigenic E. coli was found in immunized piglets. |
| first_indexed | 2024-04-10T08:03:13Z |
| format | Article |
| id | doaj.art-a4c431df41384e9db96b1bb606f53256 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:03:13Z |
| publishDate | 2005-07-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-a4c431df41384e9db96b1bb606f532562023-02-23T03:49:16ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922005-07-0150731532010.17221/5629-VETMEDvet-200507-0005Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factorsP. Alexa0J. Hamrik1K. Stouracova2E. Salajka3Veterinary Research Institute, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicExperiments were focused on the prevention of diarrhoea in weaned piglets by means of enterotoxigenic strains of Escherichia coli (ETEC) with colonizing factors K88 (F4). The process of immunization consisted of intramuscular administration of ETEC strain bacterin one day prior to weaning and oral administration of a live culture of non-pathogenic E. coli strain containing colonizing factors (O149:K88; STa-, LT-) in 3 hours after weaning. The shedding of the K88 positive E. coli strains was monitored for 3 weeks after weaning by the culture of rectal swabs. The efficacy of such immunization protocol was tested by challenge exposure to enterotoxigenic E. coli O149:K88, LT+ strain on the third or the tenth day after weaning. Following the oral administration of non-pathogenic E. coli strain containing colonizing factors K88 to piglets, the shedding of the administered strain continued for 9 days. No or very small protection against diarrhoea following the challenge exposure to enterotoxigenic E. coli was found in immunized piglets.https://vetmed.agriculturejournals.cz/artkey/vet-200507-0005_oral-immunization-against-enterotoxigenic-colibacillosis-in-weaned-piglets-by-non-pathogenic-escherichia-colist.phppigletdiarrhoea after weaningmucosal immunityf4 fimbriaek88 |
| spellingShingle | P. Alexa J. Hamrik K. Stouracova E. Salajka Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors Veterinární Medicína piglet diarrhoea after weaning mucosal immunity f4 fimbriae k88 |
| title | Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors |
| title_full | Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors |
| title_fullStr | Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors |
| title_full_unstemmed | Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors |
| title_short | Oral immunization against enterotoxigenic colibacillosis in weaned piglets by non-pathogenic Escherichia colistrain with K88 (F4) colonizing factors |
| title_sort | oral immunization against enterotoxigenic colibacillosis in weaned piglets by non pathogenic escherichia colistrain with k88 f4 colonizing factors |
| topic | piglet diarrhoea after weaning mucosal immunity f4 fimbriae k88 |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-200507-0005_oral-immunization-against-enterotoxigenic-colibacillosis-in-weaned-piglets-by-non-pathogenic-escherichia-colist.php |
| work_keys_str_mv | AT palexa oralimmunizationagainstenterotoxigeniccolibacillosisinweanedpigletsbynonpathogenicescherichiacolistrainwithk88f4colonizingfactors AT jhamrik oralimmunizationagainstenterotoxigeniccolibacillosisinweanedpigletsbynonpathogenicescherichiacolistrainwithk88f4colonizingfactors AT kstouracova oralimmunizationagainstenterotoxigeniccolibacillosisinweanedpigletsbynonpathogenicescherichiacolistrainwithk88f4colonizingfactors AT esalajka oralimmunizationagainstenterotoxigeniccolibacillosisinweanedpigletsbynonpathogenicescherichiacolistrainwithk88f4colonizingfactors |