Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved]
Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of disease. However, serotype replacement and the emerg...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-12-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/12-435/v2 |
| _version_ | 1827374251466817536 |
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| author | Ahmed H. Radhi Delan Ikram Haider N. Dawood Ali H. Al-Jumaili Ali Al-Jabban |
| author_facet | Ahmed H. Radhi Delan Ikram Haider N. Dawood Ali H. Al-Jumaili Ali Al-Jabban |
| author_sort | Ahmed H. Radhi |
| collection | DOAJ |
| description | Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of disease. However, serotype replacement and the emergence of non-vaccine serotypes as well as the persistence of a few vaccine serotypes underscores the need for development of new and effective vaccines against such pneumococcal serotypes. In the Middle East, places of religious mass gatherings are a hotspot for disease transmission in addition to the global risk factors. Therefore, the periodic surveillance of pneumococcal serotypes circulating in the region to determine the effectiveness of existing prevention strategies and develop improved vaccines is warranted. Currently, there is a lack of serotype prevalence data for Iraq due to inadequate surveillance in the region. Thus, this review aims to determine the pneumococcal serotypes circulating in Iraq which may help in the development and introduction of improved pneumococcal vaccines in the country. |
| first_indexed | 2024-03-08T11:30:16Z |
| format | Article |
| id | doaj.art-a4c86c285bc3433dbfdf55626d04a519 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-08T11:30:16Z |
| publishDate | 2023-12-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-a4c86c285bc3433dbfdf55626d04a5192024-01-26T01:00:05ZengF1000 Research LtdF1000Research2046-14022023-12-0112160249Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved]Ahmed H. Radhi0https://orcid.org/0000-0003-2703-1539Delan Ikram1https://orcid.org/0009-0000-3794-1371Haider N. Dawood2Ali H. Al-Jumaili3https://orcid.org/0000-0002-5731-4890Ali Al-Jabban4F.i.c.m.s/ C.M, Center for disease control and prevention, Baghdad, IraqPfizer, Baghdad, IraqAl Immamin al kadhimin Medical City, Baghdad, 10011, IraqMerit consultant pediatrician, Baghdad, 10011, IraqPfizer, Baghdad, IraqPneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of disease. However, serotype replacement and the emergence of non-vaccine serotypes as well as the persistence of a few vaccine serotypes underscores the need for development of new and effective vaccines against such pneumococcal serotypes. In the Middle East, places of religious mass gatherings are a hotspot for disease transmission in addition to the global risk factors. Therefore, the periodic surveillance of pneumococcal serotypes circulating in the region to determine the effectiveness of existing prevention strategies and develop improved vaccines is warranted. Currently, there is a lack of serotype prevalence data for Iraq due to inadequate surveillance in the region. Thus, this review aims to determine the pneumococcal serotypes circulating in Iraq which may help in the development and introduction of improved pneumococcal vaccines in the country.https://f1000research.com/articles/12-435/v2Iraq Pneumococcal disease Pneumococcal serotypes Pneumococcal vaccines Serotype replacementeng |
| spellingShingle | Ahmed H. Radhi Delan Ikram Haider N. Dawood Ali H. Al-Jumaili Ali Al-Jabban Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] F1000Research Iraq Pneumococcal disease Pneumococcal serotypes Pneumococcal vaccines Serotype replacement eng |
| title | Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] |
| title_full | Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] |
| title_fullStr | Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] |
| title_full_unstemmed | Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] |
| title_short | Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development [version 2; peer review: 2 approved] |
| title_sort | emerging pneumococcal serotypes in iraq scope for improved vaccine development version 2 peer review 2 approved |
| topic | Iraq Pneumococcal disease Pneumococcal serotypes Pneumococcal vaccines Serotype replacement eng |
| url | https://f1000research.com/articles/12-435/v2 |
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