The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury

The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury

Abstract Background Stress is implicated in various pathological conditions leading to liver injury. Existing evidence suggests that excessive stress can induce mitochondrial damage in hepatocytes, yet the underlying mechanism remains unclear. Ceramide synthase 6 (CerS6)-derived C16:0 ceramide is re...

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Bibliographic Details
Main Authors: Yichang Liu, Zhaoling Sun, Qiuli Sun, Li Wang, Chuan Wang, Yingmin Li, Chunling Ma, Weibo Shi, Guozhong Zhang, Yiming Dong, Xiaojing Zhang, Bin Cong
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Lipids in Health and Disease
Subjects:
Liver
Stress
Ceramide synthase 6
Ceramide
Mitochondria
Cytochrome c
Online Access:https://doi.org/10.1186/s12944-024-02019-x

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