Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus
Purpose: The aim of this study was to assess the correlation of hemoglobin A1c (HbA1c) levels with choroidal thickness in patients with type 2 diabetes mellitus (DM) using spectral domain optical coherence tomography (SD-OCT). Methods: In this prospective case series, 180 eyes from 90 patients...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Knowledge E
2019-07-01
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| Series: | Journal of Ophthalmic & Vision Research |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/jovr.v14i3.4784 |
| _version_ | 1811192816442802176 |
|---|---|
| author | Hamidreza Torabi Mohsen Saberi Isfeedvajani Majid Ramezani Seyed-Hashem Daryabari |
| author_facet | Hamidreza Torabi Mohsen Saberi Isfeedvajani Majid Ramezani Seyed-Hashem Daryabari |
| author_sort | Hamidreza Torabi |
| collection | DOAJ |
| description | Purpose: The aim of this study was to assess the correlation of hemoglobin A1c (HbA1c) levels with choroidal thickness in patients with type 2 diabetes mellitus (DM) using spectral domain optical coherence tomography (SD-OCT).
Methods: In this prospective case series, 180 eyes from 90 patients with type 2 DM were classified into three study groups based on HbA1c values: group 1 included patients with good glycemic control (HbA1c
≤
7%), group 2 included patients with moderate glycemic control (HbA1c between 7% and 8%), and group 3 included patients with poor glycemic control (HbA1c
≥
8%). Additionally, 50 eyes from 25 non-diabetic subjects were enrolled to group 4 as a control group. Sub-foveal, nasal, and temporal choroidal thickness were measured and compared.
Results: Mean central, nasal, and temporal choroidal thicknesses in diabetic patients (247.80, 238.63, and 239.30
μ
m) were significantly less than non-diabetic healthy subjects (277.56, 262.92, and 266.32
μ
m). Additionally, mean central, nasal, and temporal choroidal thickness values in group 4 (277.56, 262.92, and 266.32
μ
m) were significantly greater than the corresponding values in group 2 (248.34, 237.55, and 236.45
μ
m) and group 3 (239.81, 234.62, and 233.94
μ
m), but was not significantly different from corresponding values in group 1 (259.46, 246.12, and 251.00
μ
m).
Conclusion: HbA1c values have a significant correlation with choroidal thickness in diabetic patients, and better glycemic control with HbA1c
≤
7% may prevent choroidal thinning. |
| first_indexed | 2024-04-11T23:58:46Z |
| format | Article |
| id | doaj.art-a4ca815078754b669fca401fa32d7f61 |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-11T23:58:46Z |
| publishDate | 2019-07-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-a4ca815078754b669fca401fa32d7f612022-12-22T03:56:17ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2019-07-01141610.18502/jovr.v14i3.4784jovr.v14i3.4784Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes MellitusHamidreza TorabiMohsen Saberi IsfeedvajaniMajid RamezaniSeyed-Hashem DaryabariPurpose: The aim of this study was to assess the correlation of hemoglobin A1c (HbA1c) levels with choroidal thickness in patients with type 2 diabetes mellitus (DM) using spectral domain optical coherence tomography (SD-OCT). Methods: In this prospective case series, 180 eyes from 90 patients with type 2 DM were classified into three study groups based on HbA1c values: group 1 included patients with good glycemic control (HbA1c ≤ 7%), group 2 included patients with moderate glycemic control (HbA1c between 7% and 8%), and group 3 included patients with poor glycemic control (HbA1c ≥ 8%). Additionally, 50 eyes from 25 non-diabetic subjects were enrolled to group 4 as a control group. Sub-foveal, nasal, and temporal choroidal thickness were measured and compared. Results: Mean central, nasal, and temporal choroidal thicknesses in diabetic patients (247.80, 238.63, and 239.30 μ m) were significantly less than non-diabetic healthy subjects (277.56, 262.92, and 266.32 μ m). Additionally, mean central, nasal, and temporal choroidal thickness values in group 4 (277.56, 262.92, and 266.32 μ m) were significantly greater than the corresponding values in group 2 (248.34, 237.55, and 236.45 μ m) and group 3 (239.81, 234.62, and 233.94 μ m), but was not significantly different from corresponding values in group 1 (259.46, 246.12, and 251.00 μ m). Conclusion: HbA1c values have a significant correlation with choroidal thickness in diabetic patients, and better glycemic control with HbA1c ≤ 7% may prevent choroidal thinning.https://doi.org/10.18502/jovr.v14i3.4784Choroidal ThicknessDiabetes MellitusDiabetic RetinopathyEnhanced Depth Imaging Optical Coherence TomographyHbA1c |
| spellingShingle | Hamidreza Torabi Mohsen Saberi Isfeedvajani Majid Ramezani Seyed-Hashem Daryabari Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus Journal of Ophthalmic & Vision Research Choroidal Thickness Diabetes Mellitus Diabetic Retinopathy Enhanced Depth Imaging Optical Coherence Tomography HbA1c |
| title | Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus |
| title_full | Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus |
| title_fullStr | Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus |
| title_short | Choroidal Thickness and Hemoglobin A1c Levels in Patients with Type 2 Diabetes Mellitus |
| title_sort | choroidal thickness and hemoglobin a1c levels in patients with type 2 diabetes mellitus |
| topic | Choroidal Thickness Diabetes Mellitus Diabetic Retinopathy Enhanced Depth Imaging Optical Coherence Tomography HbA1c |
| url | https://doi.org/10.18502/jovr.v14i3.4784 |
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