Alterations in fecal β-defensin-3 secretion as a marker of instability of the gut microbiota

ABSTRACTCompositional changes in the microbiota (dysbiosis) may be a basis for Irritable Bowel Syndrome (IBS), but biomarkers are currently unavailable to direct microbiota-directed therapy. We therefore examined whether changes in fecal β-defensin could be a marker of dysbiosis in a murine model. E...

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Bibliographic Details
Main Authors: Zarwa Saqib, Giada De Palma, Jun Lu, Michael Surette, Premysl Bercik, Stephen Michael Collins
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2233679