Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation
Highlights Keloid formation is common among individuals of African ancestry. Lp(a) and OxPL are associated with acute and chronic CVD events. Lp(a) and OxPL-apoB levels are elevated in patients with keloids. Keloids express OxPL staining but not Lp(a) staining. OxPL on Lp(a) may be mechanistically i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-11-01
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| Series: | Lipids in Health and Disease |
| Online Access: | https://doi.org/10.1186/s12944-022-01720-z |
| _version_ | 1797984629170372608 |
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| author | Sundeep Ruder Brett Mansfield Andrew Ronald Immelman Nissi Varki Phuong Miu Frederick Raal Sotirios Tsimikas |
| author_facet | Sundeep Ruder Brett Mansfield Andrew Ronald Immelman Nissi Varki Phuong Miu Frederick Raal Sotirios Tsimikas |
| author_sort | Sundeep Ruder |
| collection | DOAJ |
| description | Highlights Keloid formation is common among individuals of African ancestry. Lp(a) and OxPL are associated with acute and chronic CVD events. Lp(a) and OxPL-apoB levels are elevated in patients with keloids. Keloids express OxPL staining but not Lp(a) staining. OxPL on Lp(a) may be mechanistically involved in keloid formation. |
| first_indexed | 2024-04-11T07:04:42Z |
| format | Article |
| id | doaj.art-a4ccf65eedb543e2919bd23cae8248fa |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-04-11T07:04:42Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-a4ccf65eedb543e2919bd23cae8248fa2022-12-22T04:38:25ZengBMCLipids in Health and Disease1476-511X2022-11-012111810.1186/s12944-022-01720-zLp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formationSundeep Ruder0Brett Mansfield1Andrew Ronald Immelman2Nissi Varki3Phuong Miu4Frederick Raal5Sotirios Tsimikas6Carbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the WitwatersrandCarbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the WitwatersrandCarbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the WitwatersrandDepartment of Pathology, University of CaliforniaSulpizio Cardiovascular Center, Division of Cardiovascular Medicine, University of CaliforniaCarbohydrate & Lipid Metabolism Research Unit, Faculty of Health Sciences, University of the WitwatersrandSulpizio Cardiovascular Center, Division of Cardiovascular Medicine, University of CaliforniaHighlights Keloid formation is common among individuals of African ancestry. Lp(a) and OxPL are associated with acute and chronic CVD events. Lp(a) and OxPL-apoB levels are elevated in patients with keloids. Keloids express OxPL staining but not Lp(a) staining. OxPL on Lp(a) may be mechanistically involved in keloid formation.https://doi.org/10.1186/s12944-022-01720-z |
| spellingShingle | Sundeep Ruder Brett Mansfield Andrew Ronald Immelman Nissi Varki Phuong Miu Frederick Raal Sotirios Tsimikas Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation Lipids in Health and Disease |
| title | Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation |
| title_full | Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation |
| title_fullStr | Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation |
| title_full_unstemmed | Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation |
| title_short | Lp(a), oxidized phospholipids and oxidation-specific epitopes are increased in subjects with keloid formation |
| title_sort | lp a oxidized phospholipids and oxidation specific epitopes are increased in subjects with keloid formation |
| url | https://doi.org/10.1186/s12944-022-01720-z |
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