Physical activity and risk of age-related cataract
AIM: To summarize quantitatively the prospective association between physical activity and age-related cataract (ARC) risk. METHODS: PubMed, Embase, Web of Science, and Cochrane Library were systematically searched for all relevant follow up studies until July 2019. Multivariable-adjusted relative...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2020-04-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.cn/en_publish/2020/4/20200418.pdf |
| _version_ | 1818026664340226048 |
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| author | Hong Jiang Li-Na Wang Yan Liu Ming Li Min Wu Yue Yin Le Ma Chang-Rui Wu |
| author_facet | Hong Jiang Li-Na Wang Yan Liu Ming Li Min Wu Yue Yin Le Ma Chang-Rui Wu |
| author_sort | Hong Jiang |
| collection | DOAJ |
| description | AIM: To summarize quantitatively the prospective association between physical activity and age-related cataract (ARC) risk.
METHODS: PubMed, Embase, Web of Science, and Cochrane Library were systematically searched for all relevant follow up studies until July 2019. Multivariable-adjusted relative risks (RRs) and corresponding 95% confidence intervals (CIs) from individual studies were used to calculate the overall summary estimates. The dose-response relationship was assessed using generalized least-squares trend estimation.
RESULTS: Six prospective cohort studies, involving 19 173 cases in 6.2-12.1y follow up of 171 620 participants, were included in the analysis. Increased physical activity was significantly associated with reduced risk of ARC by 10% (RR: 0.90; 95%CI: 0.81, 0.99, P=0.04). Stratified analysis by assessment method for physical activity suggest that studies using metabolic equivalent (MET) per day tended to report a slightly stronger association with ARC (RR: 0.85; 95%CI: 0.81, 0.90, P<0.001) than studies which assessed activity by weekly activity (RR: 0.96; 95%CI: 0.89, 1.03, P=0.24). Dose-response analysis indicated that the risk of ARC decreased by 2% (RR: 0.98; 95%CI: 0.98, 0.99, P<0.001) for every 6 METs per day increase in activity.
CONCLUSION: The findings from this Meta-analysis provide additional evidence that increased physical activity is inversely associated with ARC risk dose-responsively. |
| first_indexed | 2024-12-10T04:35:36Z |
| format | Article |
| id | doaj.art-a4cf35ac10f04173898a846576d59236 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-10T04:35:36Z |
| publishDate | 2020-04-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-a4cf35ac10f04173898a846576d592362022-12-22T02:02:02ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982020-04-0113464364910.18240/ijo.2020.04.18Physical activity and risk of age-related cataractHong Jiang0Li-Na Wang1Yan Liu2Ming Li3Min Wu4Yue Yin5Le Ma6Chang-Rui Wu7First Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061, Shaanxi Province, China; School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaSchool of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaSchool of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaCentre for Population Health Research, Division of Health Sciences, University of South Australia, Adelaide, SA 5001, AustraliaSchool of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaSchool of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaSchool of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an 710061, Shaanxi Province, ChinaFirst Affiliated Hospital, Xi’an Jiaotong University College of Medicine, Xi’an 710061, Shaanxi Province, ChinaAIM: To summarize quantitatively the prospective association between physical activity and age-related cataract (ARC) risk. METHODS: PubMed, Embase, Web of Science, and Cochrane Library were systematically searched for all relevant follow up studies until July 2019. Multivariable-adjusted relative risks (RRs) and corresponding 95% confidence intervals (CIs) from individual studies were used to calculate the overall summary estimates. The dose-response relationship was assessed using generalized least-squares trend estimation. RESULTS: Six prospective cohort studies, involving 19 173 cases in 6.2-12.1y follow up of 171 620 participants, were included in the analysis. Increased physical activity was significantly associated with reduced risk of ARC by 10% (RR: 0.90; 95%CI: 0.81, 0.99, P=0.04). Stratified analysis by assessment method for physical activity suggest that studies using metabolic equivalent (MET) per day tended to report a slightly stronger association with ARC (RR: 0.85; 95%CI: 0.81, 0.90, P<0.001) than studies which assessed activity by weekly activity (RR: 0.96; 95%CI: 0.89, 1.03, P=0.24). Dose-response analysis indicated that the risk of ARC decreased by 2% (RR: 0.98; 95%CI: 0.98, 0.99, P<0.001) for every 6 METs per day increase in activity. CONCLUSION: The findings from this Meta-analysis provide additional evidence that increased physical activity is inversely associated with ARC risk dose-responsively.http://www.ijo.cn/en_publish/2020/4/20200418.pdfphysical activityage-related cataractlensmeta-analysis |
| spellingShingle | Hong Jiang Li-Na Wang Yan Liu Ming Li Min Wu Yue Yin Le Ma Chang-Rui Wu Physical activity and risk of age-related cataract International Journal of Ophthalmology physical activity age-related cataract lens meta-analysis |
| title | Physical activity and risk of age-related cataract |
| title_full | Physical activity and risk of age-related cataract |
| title_fullStr | Physical activity and risk of age-related cataract |
| title_full_unstemmed | Physical activity and risk of age-related cataract |
| title_short | Physical activity and risk of age-related cataract |
| title_sort | physical activity and risk of age related cataract |
| topic | physical activity age-related cataract lens meta-analysis |
| url | http://www.ijo.cn/en_publish/2020/4/20200418.pdf |
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