Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate
α-tricalcium (α-TCP) phosphate is widely used as an osteoinductive biocompatible material, serving as an alternative to synthetic porous bone materials. The objective of this study is to obtain a highly filled fibrous nonwoven material composed of poly-3-hydroxybutyrate (PHB) and α-TCP and to invest...
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MDPI AG
2023-07-01
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author | Polina M. Tyubaeva Kristina G. Gasparyan Alexander Yu. Fedotov Pavel V. Lobzhanidze Oleg V. Baranov Alexey A. Egorov Vladimir P. Sirotinkin Vladimir S. Komlev Anatoly A. Olkhov |
author_facet | Polina M. Tyubaeva Kristina G. Gasparyan Alexander Yu. Fedotov Pavel V. Lobzhanidze Oleg V. Baranov Alexey A. Egorov Vladimir P. Sirotinkin Vladimir S. Komlev Anatoly A. Olkhov |
author_sort | Polina M. Tyubaeva |
collection | DOAJ |
description | α-tricalcium (α-TCP) phosphate is widely used as an osteoinductive biocompatible material, serving as an alternative to synthetic porous bone materials. The objective of this study is to obtain a highly filled fibrous nonwoven material composed of poly-3-hydroxybutyrate (PHB) and α-TCP and to investigate the morphology, structure, and properties of the composite obtained by the electrospinning method (ES). The addition of α-TCP had a significant effect on the supramolecular structure of the material, allowing it to control the crystallinity of the material, which was accompanied by changes in mechanical properties, FTIR spectra, and XRD curves. The obtained results open the way to the creation of new osteoconductive materials with a controlled release of the source of calcium into the living organism. |
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issn | 2073-4360 |
language | English |
last_indexed | 2024-03-11T00:18:40Z |
publishDate | 2023-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Polymers |
spelling | doaj.art-a4d24e432ca342249b75566e4a65e58d2023-11-18T23:27:32ZengMDPI AGPolymers2073-43602023-07-011515316710.3390/polym15153167Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium PhosphatePolina M. Tyubaeva0Kristina G. Gasparyan1Alexander Yu. Fedotov2Pavel V. Lobzhanidze3Oleg V. Baranov4Alexey A. Egorov5Vladimir P. Sirotinkin6Vladimir S. Komlev7Anatoly A. Olkhov8Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, RussiaDepartment of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaA.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, RussiaDepartment of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russiaα-tricalcium (α-TCP) phosphate is widely used as an osteoinductive biocompatible material, serving as an alternative to synthetic porous bone materials. The objective of this study is to obtain a highly filled fibrous nonwoven material composed of poly-3-hydroxybutyrate (PHB) and α-TCP and to investigate the morphology, structure, and properties of the composite obtained by the electrospinning method (ES). The addition of α-TCP had a significant effect on the supramolecular structure of the material, allowing it to control the crystallinity of the material, which was accompanied by changes in mechanical properties, FTIR spectra, and XRD curves. The obtained results open the way to the creation of new osteoconductive materials with a controlled release of the source of calcium into the living organism.https://www.mdpi.com/2073-4360/15/15/3167poly-3-hydroxybutyrateα-tricalcium phosphatefibrous nonwoven materialelectrospinning |
spellingShingle | Polina M. Tyubaeva Kristina G. Gasparyan Alexander Yu. Fedotov Pavel V. Lobzhanidze Oleg V. Baranov Alexey A. Egorov Vladimir P. Sirotinkin Vladimir S. Komlev Anatoly A. Olkhov Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate Polymers poly-3-hydroxybutyrate α-tricalcium phosphate fibrous nonwoven material electrospinning |
title | Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate |
title_full | Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate |
title_fullStr | Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate |
title_full_unstemmed | Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate |
title_short | Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate |
title_sort | development of nonwoven fibrous materials based on poly 3 hydroxybutyrate with a high content of α tricalcium phosphate |
topic | poly-3-hydroxybutyrate α-tricalcium phosphate fibrous nonwoven material electrospinning |
url | https://www.mdpi.com/2073-4360/15/15/3167 |
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