Bacterial flora on the surface of oral squamous cell carcinoma
Background: The aim of the study was to determine the microbial presence and type in the biofilms present on the surface of oral squamous cell carcinomas and benign lesions of oral mucosa. Methods: Thirty new (untreated) patients with oral squamous cell carcinoma were examined. The control...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institute of Oncology, Sremska Kamenica, Serbia
2013-01-01
|
| Series: | Archive of Oncology |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-7310/2013/0354-73101302062C.pdf |
| Summary: | Background: The aim of the study was to determine the microbial presence and
type in the biofilms present on the surface of oral squamous cell carcinomas
and benign lesions of oral mucosa. Methods: Thirty new (untreated) patients
with oral squamous cell carcinoma were examined. The control group consisted
of thirty subjects with benign lesions of oral mucosa. Swab samples were
taken from the superficial layer of the carcinoma and benign lesions for
bacteriological examination. Swabs were transported within 2 hours and
immediately sown and incubated. Oral health index was assessed in all
patients. Results: The prevalence of pathological bacterial microflora was
significantly higher in cancer patients (p<0.01). No significant associations
were found between bacterial presence and gender, localization, cigarette
smoking, alcohol consumption and denture wearing (p>0.05). Poor oral hygiene
was also registered in cancer patients. Conclusion: Possibility of microflora
retention on irregular oral carcinoma surface possibly contributes to chronic
inflammation often observed on the surface of oral carcinomas. |
|---|---|
| ISSN: | 0354-7310 1450-9520 |