Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study
Abstract The authors aim to assess the correlation between hypertension and the triglyceride‐glucose (TyG) index and its associated indices, and to compare their abilities to identify hypertension. Four thousand eight hundred and sixty‐six non‐hypertensive participants were enrolled from the China N...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | The Journal of Clinical Hypertension |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jch.14758 |
| _version_ | 1827379316464287744 |
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| author | Changqiang Yang Yue Song Xinquan Wang Yi Yang Yaqiong Zhou Dan Wang Jixin Hou Peijian Wang |
| author_facet | Changqiang Yang Yue Song Xinquan Wang Yi Yang Yaqiong Zhou Dan Wang Jixin Hou Peijian Wang |
| author_sort | Changqiang Yang |
| collection | DOAJ |
| description | Abstract The authors aim to assess the correlation between hypertension and the triglyceride‐glucose (TyG) index and its associated indices, and to compare their abilities to identify hypertension. Four thousand eight hundred and sixty‐six non‐hypertensive participants were enrolled from the China National Health Survey in 2009. The data on new‐onset hypertension were gathered in both 2011 and 2015. The TyG index and its associated indices were derived from the fasting triglyceride, blood glucose levels, and anthropometric parameters. Multivariate logistic regression analyses and receiver operating characteristic curve analysis were used. The adjusted odds ratio (OR) and 95% confidence interval (CI) for the new‐onset hypertension for the TyG‐waist‐to‐height ratio (TyG‐WHtR), TyG‐waist circumference (TyG‐WC), TyG‐waist‐to‐hip ratio (TyG‐WHR), TyG‐body mass index (TyG‐BMI), and TyG index were 1.379 (1.230–1.546), 1.002 (1.001–1.003), 1.156 (1.069–1.251), 1.007 (1.005–1.009), and 1.187 (1.051–1.341), respectively. In addition, comparing the lowest quartile (Q1) group with the highest quartile (Q4), the adjusted OR and 95% CI for the new‐onset hypertension were found to be 1.86 (1.48–2.35), 1.93 (1.53–2.43), 1.71 (1.36–2.16), 2.00 (1.60–2.50), and 1.49 (1.19–1.88) for TyG‐WHtR, TyG‐WC, TyG‐WHR, TyG‐BMI, and TyG index, respectively, among all participants. The TyG‐WHtR had the largest area under the curve (AUC) for hypertension (AUC, 0.628; 95% CI, 0.614–0.641) in all participants. Stratified analysis also indicated that the TyG‐WHtR exhibited the greatest AUC in both males (AUC, 0.608; 95% CI, 0.587–0.629) and females (AUC, 0.648; 95% CI, 0.629–0.666). In conclusions, the TyG index and its associated indices were positively associated with hypertension. Among these indices, TyG‐WHtR was the most valuable indicator for predicting hypertension. |
| first_indexed | 2024-03-08T13:11:31Z |
| format | Article |
| id | doaj.art-a4d5af9c4a0d416099ae3edb1960121b |
| institution | Directory Open Access Journal |
| issn | 1524-6175 1751-7176 |
| language | English |
| last_indexed | 2024-03-08T13:11:31Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj.art-a4d5af9c4a0d416099ae3edb1960121b2024-01-18T11:56:09ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762024-01-01261536210.1111/jch.14758Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort studyChangqiang Yang0Yue Song1Xinquan Wang2Yi Yang3Yaqiong Zhou4Dan Wang5Jixin Hou6Peijian Wang7Department of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Pediatrics the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaDepartment of Cardiology the First Affiliated Hospital, Chengdu Medical College Chengdu Sichuan ChinaAbstract The authors aim to assess the correlation between hypertension and the triglyceride‐glucose (TyG) index and its associated indices, and to compare their abilities to identify hypertension. Four thousand eight hundred and sixty‐six non‐hypertensive participants were enrolled from the China National Health Survey in 2009. The data on new‐onset hypertension were gathered in both 2011 and 2015. The TyG index and its associated indices were derived from the fasting triglyceride, blood glucose levels, and anthropometric parameters. Multivariate logistic regression analyses and receiver operating characteristic curve analysis were used. The adjusted odds ratio (OR) and 95% confidence interval (CI) for the new‐onset hypertension for the TyG‐waist‐to‐height ratio (TyG‐WHtR), TyG‐waist circumference (TyG‐WC), TyG‐waist‐to‐hip ratio (TyG‐WHR), TyG‐body mass index (TyG‐BMI), and TyG index were 1.379 (1.230–1.546), 1.002 (1.001–1.003), 1.156 (1.069–1.251), 1.007 (1.005–1.009), and 1.187 (1.051–1.341), respectively. In addition, comparing the lowest quartile (Q1) group with the highest quartile (Q4), the adjusted OR and 95% CI for the new‐onset hypertension were found to be 1.86 (1.48–2.35), 1.93 (1.53–2.43), 1.71 (1.36–2.16), 2.00 (1.60–2.50), and 1.49 (1.19–1.88) for TyG‐WHtR, TyG‐WC, TyG‐WHR, TyG‐BMI, and TyG index, respectively, among all participants. The TyG‐WHtR had the largest area under the curve (AUC) for hypertension (AUC, 0.628; 95% CI, 0.614–0.641) in all participants. Stratified analysis also indicated that the TyG‐WHtR exhibited the greatest AUC in both males (AUC, 0.608; 95% CI, 0.587–0.629) and females (AUC, 0.648; 95% CI, 0.629–0.666). In conclusions, the TyG index and its associated indices were positively associated with hypertension. Among these indices, TyG‐WHtR was the most valuable indicator for predicting hypertension.https://doi.org/10.1111/jch.14758Chinese populationhypertensioninsulin resistanceTyG indexTyG‐WHtR |
| spellingShingle | Changqiang Yang Yue Song Xinquan Wang Yi Yang Yaqiong Zhou Dan Wang Jixin Hou Peijian Wang Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study The Journal of Clinical Hypertension Chinese population hypertension insulin resistance TyG index TyG‐WHtR |
| title | Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study |
| title_full | Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study |
| title_fullStr | Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study |
| title_full_unstemmed | Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study |
| title_short | Association of hypertension with the triglyceride–glucose index and its associated indices in the Chinese population: A 6‐year prospective cohort study |
| title_sort | association of hypertension with the triglyceride glucose index and its associated indices in the chinese population a 6 year prospective cohort study |
| topic | Chinese population hypertension insulin resistance TyG index TyG‐WHtR |
| url | https://doi.org/10.1111/jch.14758 |
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