Eosinophilic granuloma of the occipital bone in an adult: A case report
Eosinophilic granuloma (EG) refers to the most common and benign form of the disorder known as Langerhans’ cell histiocytosis. The disease is typically found in children and adolescents and rarely affects adults. We present a case of EG in the occipital bone in a 36-year-old man, who visited our hos...
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| Format: | Article |
| Language: | English |
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Wiley
2011-02-01
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| Series: | Kaohsiung Journal of Medical Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X1000029X |
| _version_ | 1819259004101066752 |
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| author | Joon-Khim Loh Yu-Feng Su Shiuh-Lin Hwang Chee-Yin Chai Shen-Long Howng Ann-Shung Lieu 羅永欽 蘇裕峯 黃旭霖 蔡志仁 洪純隆 劉安祥 |
| author_facet | Joon-Khim Loh Yu-Feng Su Shiuh-Lin Hwang Chee-Yin Chai Shen-Long Howng Ann-Shung Lieu 羅永欽 蘇裕峯 黃旭霖 蔡志仁 洪純隆 劉安祥 |
| author_sort | Joon-Khim Loh |
| collection | DOAJ |
| description | Eosinophilic granuloma (EG) refers to the most common and benign form of the disorder known as Langerhans’ cell histiocytosis. The disease is typically found in children and adolescents and rarely affects adults. We present a case of EG in the occipital bone in a 36-year-old man, who visited our hospital with the chief complaint of left occipital palpable tumor mass with local tenderness and pain for one month. An X-ray of the skull revealed a rounded osteolytic lesion. A computed tomography scan revealed a shadow of soft tissues in the left occipital site involving the entire thickness of the calvaria, which was indicative of marked destruction of the bone. The soft mass was successfully removed. The margins of the skull lesion were excised, and cranioplasty was performed simultaneously with bone cement. A definitive diagnosis of EG was made by histopathology and immunohistochemical detection of S-100 antigen in the tissue samples. With respect to management, we believe surgery is the best option for most accessible cranial lesions of EG. A cranioplasty with bone cement or autologous bone can be performed in the same session to repair the cranial defect. |
| first_indexed | 2024-12-23T19:03:07Z |
| format | Article |
| id | doaj.art-a4da799163474cfc89647c3b1602e816 |
| institution | Directory Open Access Journal |
| issn | 1607-551X |
| language | English |
| last_indexed | 2024-12-23T19:03:07Z |
| publishDate | 2011-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Kaohsiung Journal of Medical Sciences |
| spelling | doaj.art-a4da799163474cfc89647c3b1602e8162022-12-21T17:34:40ZengWileyKaohsiung Journal of Medical Sciences1607-551X2011-02-01272767910.1016/j.kjms.2010.05.004Eosinophilic granuloma of the occipital bone in an adult: A case reportJoon-Khim Loh0Yu-Feng Su1Shiuh-Lin Hwang2Chee-Yin Chai3Shen-Long Howng4Ann-Shung Lieu5羅永欽6蘇裕峯7黃旭霖8蔡志仁9洪純隆10劉安祥11Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanFaculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanFaculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanDivision of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, TaiwanEosinophilic granuloma (EG) refers to the most common and benign form of the disorder known as Langerhans’ cell histiocytosis. The disease is typically found in children and adolescents and rarely affects adults. We present a case of EG in the occipital bone in a 36-year-old man, who visited our hospital with the chief complaint of left occipital palpable tumor mass with local tenderness and pain for one month. An X-ray of the skull revealed a rounded osteolytic lesion. A computed tomography scan revealed a shadow of soft tissues in the left occipital site involving the entire thickness of the calvaria, which was indicative of marked destruction of the bone. The soft mass was successfully removed. The margins of the skull lesion were excised, and cranioplasty was performed simultaneously with bone cement. A definitive diagnosis of EG was made by histopathology and immunohistochemical detection of S-100 antigen in the tissue samples. With respect to management, we believe surgery is the best option for most accessible cranial lesions of EG. A cranioplasty with bone cement or autologous bone can be performed in the same session to repair the cranial defect.http://www.sciencedirect.com/science/article/pii/S1607551X1000029XEosinophilic granulomaLangerhans’ cell histiocytosisSkull neoplasm |
| spellingShingle | Joon-Khim Loh Yu-Feng Su Shiuh-Lin Hwang Chee-Yin Chai Shen-Long Howng Ann-Shung Lieu 羅永欽 蘇裕峯 黃旭霖 蔡志仁 洪純隆 劉安祥 Eosinophilic granuloma of the occipital bone in an adult: A case report Kaohsiung Journal of Medical Sciences Eosinophilic granuloma Langerhans’ cell histiocytosis Skull neoplasm |
| title | Eosinophilic granuloma of the occipital bone in an adult: A case report |
| title_full | Eosinophilic granuloma of the occipital bone in an adult: A case report |
| title_fullStr | Eosinophilic granuloma of the occipital bone in an adult: A case report |
| title_full_unstemmed | Eosinophilic granuloma of the occipital bone in an adult: A case report |
| title_short | Eosinophilic granuloma of the occipital bone in an adult: A case report |
| title_sort | eosinophilic granuloma of the occipital bone in an adult a case report |
| topic | Eosinophilic granuloma Langerhans’ cell histiocytosis Skull neoplasm |
| url | http://www.sciencedirect.com/science/article/pii/S1607551X1000029X |
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