Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas
The objective of this study was to assess the impact of marital status on tonsil squamous cell carcinomas (TSCCs) prognosis and to analyze whether the impact is correlated with gender, age, and race. We examined the clinicopathological variables using Chi-squared tests and evaluated the association...
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2022-11-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2022-0568 |
| _version_ | 1811320210132566016 |
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| author | Li Yujiao Hu Chaosu |
| author_facet | Li Yujiao Hu Chaosu |
| author_sort | Li Yujiao |
| collection | DOAJ |
| description | The objective of this study was to assess the impact of marital status on tonsil squamous cell carcinomas (TSCCs) prognosis and to analyze whether the impact is correlated with gender, age, and race. We examined the clinicopathological variables using Chi-squared tests and evaluated the association between survival and different variables using the methods of Kaplan–Meier. Univariate and multivariate analyses were performed to determine the effects of each variable on survival. A total of 10,720 patients were analyzed. The rate of being married was higher among Asian or Caucasian, and this rate decreased with higher tumor stage. While both married male and female survivors benefit from their marital status, we found a differential in cancer-specific survival based on gender, with males benefitting more than females (p < 0.05). The same results were found in overall survival. Subgroup analysis shows that the protective effect of marriage was consistent in all patients except for N3 groups (all, p < 0.05). While there are survival benefits for married patients with TSCCs, married/partnered males may benefit more than females. Age, race, and gender could affect the correlation between marital status and survival. |
| first_indexed | 2024-04-13T12:55:03Z |
| format | Article |
| id | doaj.art-a4dc35a9c04343b8b75b6e89824944b8 |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-04-13T12:55:03Z |
| publishDate | 2022-11-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-a4dc35a9c04343b8b75b6e89824944b82022-12-22T02:46:05ZengDe GruyterOpen Medicine2391-54632022-11-011711773177910.1515/med-2022-0568Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomasLi Yujiao0Hu Chaosu1Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, ChinaDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, 270 Dong An Road, Shanghai 200032, ChinaThe objective of this study was to assess the impact of marital status on tonsil squamous cell carcinomas (TSCCs) prognosis and to analyze whether the impact is correlated with gender, age, and race. We examined the clinicopathological variables using Chi-squared tests and evaluated the association between survival and different variables using the methods of Kaplan–Meier. Univariate and multivariate analyses were performed to determine the effects of each variable on survival. A total of 10,720 patients were analyzed. The rate of being married was higher among Asian or Caucasian, and this rate decreased with higher tumor stage. While both married male and female survivors benefit from their marital status, we found a differential in cancer-specific survival based on gender, with males benefitting more than females (p < 0.05). The same results were found in overall survival. Subgroup analysis shows that the protective effect of marriage was consistent in all patients except for N3 groups (all, p < 0.05). While there are survival benefits for married patients with TSCCs, married/partnered males may benefit more than females. Age, race, and gender could affect the correlation between marital status and survival.https://doi.org/10.1515/med-2022-0568tonsil squamous cell carcinomasmarital statusgenderprognosis |
| spellingShingle | Li Yujiao Hu Chaosu Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas Open Medicine tonsil squamous cell carcinomas marital status gender prognosis |
| title | Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas |
| title_full | Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas |
| title_fullStr | Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas |
| title_full_unstemmed | Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas |
| title_short | Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas |
| title_sort | marital status and its correlation with age race and gender in prognosis of tonsil squamous cell carcinomas |
| topic | tonsil squamous cell carcinomas marital status gender prognosis |
| url | https://doi.org/10.1515/med-2022-0568 |
| work_keys_str_mv | AT liyujiao maritalstatusanditscorrelationwithageraceandgenderinprognosisoftonsilsquamouscellcarcinomas AT huchaosu maritalstatusanditscorrelationwithageraceandgenderinprognosisoftonsilsquamouscellcarcinomas |