TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM

Activity of reproductive system is under the hypothalamic and hypophysial control, defining role in development and normal functioning of gonads is played by impulsive secretion of GnRH and gonadotropins. The congenital genetic defects leading to the central hypogonadism can be found at any level of...

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Main Author: I. A. Ilovayskaya
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-05-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/871
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author I. A. Ilovayskaya
author_facet I. A. Ilovayskaya
author_sort I. A. Ilovayskaya
collection DOAJ
description Activity of reproductive system is under the hypothalamic and hypophysial control, defining role in development and normal functioning of gonads is played by impulsive secretion of GnRH and gonadotropins. The congenital genetic defects leading to the central hypogonadism can be found at any level of a hypotalamo-hypophysial axis: from disturbance of secretion of GnRH to structural defects of gonadotropins. The majority of cases are sporadic though various ways of inheritance have also been reported. The acquired hypotalamo-hypophysial disturbances can be organic and functional. Organic disorders of such lesion include different types of tumors localized at chiasmo-sellar region (first of all, pituitary tumors), consequences of surgical or radial intervention concerning these neoplasms, brain injuries and also autoimmune, infiltrative and other more rare species of diseases. Functional neuroendocrine disturbances arise against absence of visible changes of structure of a brain as the main reasons consider superfluous exercise stresses, stresses and critical depression of mass of a body
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spelling doaj.art-a4dc848c8aff491d9d5f8e6575acb9892025-01-27T16:48:36ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-05-0103(1)120126817TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEMI. A. Ilovayskaya0Moscow Regional Research and Clinical Institute named by M.F. VladimirskyActivity of reproductive system is under the hypothalamic and hypophysial control, defining role in development and normal functioning of gonads is played by impulsive secretion of GnRH and gonadotropins. The congenital genetic defects leading to the central hypogonadism can be found at any level of a hypotalamo-hypophysial axis: from disturbance of secretion of GnRH to structural defects of gonadotropins. The majority of cases are sporadic though various ways of inheritance have also been reported. The acquired hypotalamo-hypophysial disturbances can be organic and functional. Organic disorders of such lesion include different types of tumors localized at chiasmo-sellar region (first of all, pituitary tumors), consequences of surgical or radial intervention concerning these neoplasms, brain injuries and also autoimmune, infiltrative and other more rare species of diseases. Functional neuroendocrine disturbances arise against absence of visible changes of structure of a brain as the main reasons consider superfluous exercise stresses, stresses and critical depression of mass of a bodyhttps://www.actabiomedica.ru/jour/article/view/871central hypogonadotropic hypogonadismgonadotropin-releasing-hormonegonadotropinspituitary
spellingShingle I. A. Ilovayskaya
TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
Acta Biomedica Scientifica
central hypogonadotropic hypogonadism
gonadotropin-releasing-hormone
gonadotropins
pituitary
title TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
title_full TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
title_fullStr TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
title_full_unstemmed TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
title_short TUMORAL AND NON TUMORAL PITUITARY LESIONS AND REPRODUCTIVE SYSTEM
title_sort tumoral and non tumoral pituitary lesions and reproductive system
topic central hypogonadotropic hypogonadism
gonadotropin-releasing-hormone
gonadotropins
pituitary
url https://www.actabiomedica.ru/jour/article/view/871
work_keys_str_mv AT iailovayskaya tumoralandnontumoralpituitarylesionsandreproductivesystem