Programmed ribosomal frameshift alters expression of west nile virus genes and facilitates virus replication in birds and mosquitoes.

Programmed ribosomal frameshift alters expression of west nile virus genes and facilitates virus replication in birds and mosquitoes.

West Nile virus (WNV) is a human pathogen of significant medical importance with close to 40,000 cases of encephalitis and more than 1,600 deaths reported in the US alone since its first emergence in New York in 1999. Previous studies identified a motif in the beginning of non-structural gene NS2A o...

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Bibliographic Details
Main Authors: Ezequiel Balmori Melian, Sonja Hall-Mendelin, Fangyao Du, Nick Owens, Angela M Bosco-Lauth, Tomoko Nagasaki, Stephen Rudd, Aaron C Brault, Richard A Bowen, Roy A Hall, Andrew F van den Hurk, Alexander A Khromykh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4223154?pdf=render

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