Anti-cancer effects of Coix seed extract through KCTD9-mediated ubiquitination of TOP2A in lung adenocarcinoma

Anti-cancer effects of Coix seed extract through KCTD9-mediated ubiquitination of TOP2A in lung adenocarcinoma

Abstract Background Coix seed extract (CSE), a traditional Chinese medicine, has been reported as an adjunctive therapy in cancers. However, the molecular targets are largely unclear. The study is designed to unveil its function in lung adenocarcinoma (LUAD) and the possible molecular mechanism. Met...

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Bibliographic Details
Main Authors: Jiuyang Jiang, Xue Li, Chun Zhang, Jiafu Wang, Jin Li
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Division
Subjects:
Lung adenocarcinoma
Coix seed extract
KCTD9
TOP2A
Ubiquitination modification
Online Access:https://doi.org/10.1186/s13008-024-00112-2

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