MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

Abstract Background The previous studies have revealed that abnormal RNA-binding protein Musashi-2 (MSI2) expression is associated with cancer progression through post-transcriptional mechanisms, however mechanistic details of this regulation in acute myeloid leukemia (AML) still remain unclear. Our...

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Bibliographic Details
Main Authors: Fanfan Li, Yixiang Han, Rongrong Chen, Yinyan Jiang, Cheng Chen, Xiaofang Wang, Jifan Zhou, Qingqing Xu, Songfu Jiang, Si Zhang, Kang Yu, Shenghui Zhang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Translational Medicine
Subjects:
Acute myeloid leukemia
microRNA-143
Musashi-2
DLL1
Snail1
Online Access:https://doi.org/10.1186/s12967-023-04106-6

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