MV1035 Overcomes Temozolomide Resistance in Patient-Derived Glioblastoma Stem Cell Lines

MV1035 Overcomes Temozolomide Resistance in Patient-Derived Glioblastoma Stem Cell Lines

Glioblastoma (GBM, grade IV glioma) represents the most aggressive brain tumor and patients with GBM have a poor prognosis. Until now surgical resection followed by radiotherapy and temozolomide (TMZ) treatment represents the standard strategy for GBM. We showed that the imidazobenzoxazin-5-thione M...

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Bibliographic Details
Main Authors: Alessio Malacrida, Alessandro Di Domizio, Angela Bentivegna, Giacomo Cislaghi, Eleonora Messuti, Silvia Maria Tabano, Carlo Giussani, Valentina Zuliani, Mirko Rivara, Gabriella Nicolini
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biology
Subjects:
glioblastoma
temozolomide
patient-derived GSCs
ALKBH2
Online Access:https://www.mdpi.com/2079-7737/11/1/70

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