<i>APC</i> Mutations Are Not Confined to Hotspot Regions in Early-Onset Colorectal Cancer

<i>APC</i> Mutations Are Not Confined to Hotspot Regions in Early-Onset Colorectal Cancer

While overall colorectal cancer (CRC) cases have been declining worldwide there has been an increase in the incidence of the disease among patients under 50 years of age. Mutation of the <i>APC</i> gene is a common early event in CRC but is reported at lower rates in early-onset colorect...

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Bibliographic Details
Main Authors: Alan Aitchison, Christopher Hakkaart, Robert C. Day, Helen R. Morrin, Frank A. Frizelle, Jacqueline I. Keenan
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
early-onset
colorectal cancer
APC
sequencing
DNA methylation
diet
Online Access:https://www.mdpi.com/2072-6694/12/12/3829

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