Precision drugging of the MAPK pathway in head and neck cancer

Precision drugging of the MAPK pathway in head and neck cancer

Abstract The mitogen-activating protein kinase (MAPK) pathway is central for cell proliferation, differentiation, and senescence. In human, germline defects of the pathway contribute to developmental and congenital head and neck disorders. Nearly 1/5 of head and neck squamous cell carcinoma (HNSCC)...

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Bibliographic Details
Main Authors: Hoi-Lam Ngan, Chun-Ho Law, Yannie Chung Yan Choi, Jenny Yu-Sum Chan, Vivian Wai Yan Lui
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-022-00293-1

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