Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity
The paper considers the formative processes of chiral nano- and microparticles in solutions of D-aminoglucan chitosan (CS) in L- and D-aspartic acid (AspA) by means of the counterionic condensation of components and the stabilization of particles by a polysiloxane shell. The effect of the L- and D-e...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Materials Proceedings |
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| Online Access: | https://www.mdpi.com/2673-4605/14/1/31 |
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| author | Anna Shipovskaya Xenia Shipenok Tatiana Lugovitskaya Tatiana Babicheva |
| author_facet | Anna Shipovskaya Xenia Shipenok Tatiana Lugovitskaya Tatiana Babicheva |
| author_sort | Anna Shipovskaya |
| collection | DOAJ |
| description | The paper considers the formative processes of chiral nano- and microparticles in solutions of D-aminoglucan chitosan (CS) in L- and D-aspartic acid (AspA) by means of the counterionic condensation of components and the stabilization of particles by a polysiloxane shell. The effect of the L- and D-enantiomers of AspA on the structure, size, shape, and zeta potential of nano(micro)particles was studied using IR spectroscopy, dynamic light scattering, and electron and optical microscopy. It was found that chiral particles of CS·L-AspA and CS·D-AspA are non-toxic, hemo- and biocompatible, and exhibit high growth-stimulating activity in the test plants, with the best effect observed for homochiral D-glucan–D-AspA particles. |
| first_indexed | 2024-03-10T22:30:14Z |
| format | Article |
| id | doaj.art-a4f66b31725144b38df814adf73b3436 |
| institution | Directory Open Access Journal |
| issn | 2673-4605 |
| language | English |
| last_indexed | 2024-03-10T22:30:14Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials Proceedings |
| spelling | doaj.art-a4f66b31725144b38df814adf73b34362023-11-19T11:46:43ZengMDPI AGMaterials Proceedings2673-46052023-05-011413110.3390/IOCN2023-14492Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological ActivityAnna Shipovskaya0Xenia Shipenok1Tatiana Lugovitskaya2Tatiana Babicheva3Institute of Chemistry, Saratov State University, 410012 Saratov, RussiaInstitute of Chemistry, Saratov State University, 410012 Saratov, RussiaInstitute of New Materials and Technologies, Ural Federal State University, 620002 Ekaterinburg, RussiaInstitute of Chemistry, Saratov State University, 410012 Saratov, RussiaThe paper considers the formative processes of chiral nano- and microparticles in solutions of D-aminoglucan chitosan (CS) in L- and D-aspartic acid (AspA) by means of the counterionic condensation of components and the stabilization of particles by a polysiloxane shell. The effect of the L- and D-enantiomers of AspA on the structure, size, shape, and zeta potential of nano(micro)particles was studied using IR spectroscopy, dynamic light scattering, and electron and optical microscopy. It was found that chiral particles of CS·L-AspA and CS·D-AspA are non-toxic, hemo- and biocompatible, and exhibit high growth-stimulating activity in the test plants, with the best effect observed for homochiral D-glucan–D-AspA particles.https://www.mdpi.com/2673-4605/14/1/31chitosanaspartic acidL- and D-enantiomersnano(micro)particleschiralitybiological activity |
| spellingShingle | Anna Shipovskaya Xenia Shipenok Tatiana Lugovitskaya Tatiana Babicheva Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity Materials Proceedings chitosan aspartic acid L- and D-enantiomers nano(micro)particles chirality biological activity |
| title | Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity |
| title_full | Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity |
| title_fullStr | Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity |
| title_full_unstemmed | Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity |
| title_short | Self-Assembling Nano- and Microparticles of Chitosan L- and D-Aspartate: Preparation, Structure, and Biological Activity |
| title_sort | self assembling nano and microparticles of chitosan l and d aspartate preparation structure and biological activity |
| topic | chitosan aspartic acid L- and D-enantiomers nano(micro)particles chirality biological activity |
| url | https://www.mdpi.com/2673-4605/14/1/31 |
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