Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate
Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
| Series: | Indian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=136;epage=138;aulast=Dudani |
| _version_ | 1818288114201788416 |
|---|---|
| author | Sharmila Dudani Ajay Malik A S Sandhu N S Mani |
| author_facet | Sharmila Dudani Ajay Malik A S Sandhu N S Mani |
| author_sort | Sharmila Dudani |
| collection | DOAJ |
| description | Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl-CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic options |
| first_indexed | 2024-12-13T01:51:14Z |
| format | Article |
| id | doaj.art-a4fc3c9fc22b40d9aacda25215bf7eae |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-12-13T01:51:14Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-a4fc3c9fc22b40d9aacda25215bf7eae2022-12-22T00:03:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242015-01-0131213613810.4103/0970-1591.152921Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostateSharmila DudaniAjay MalikA S SandhuN S ManiCarcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl-CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic optionshttp://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=136;epage=138;aulast=Dudaniα-methyl-CoA-racemasecarcinosarcoma prostatepseudohyperplastic variant |
| spellingShingle | Sharmila Dudani Ajay Malik A S Sandhu N S Mani Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate Indian Journal of Urology α-methyl-CoA-racemase carcinosarcoma prostate pseudohyperplastic variant |
| title | Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate |
| title_full | Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate |
| title_fullStr | Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate |
| title_full_unstemmed | Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate |
| title_short | Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate |
| title_sort | pseudohyperplastic variant of adenocarcinoma as a component of α methyl coa racemase amacr negative carcinosarcoma of the prostate |
| topic | α-methyl-CoA-racemase carcinosarcoma prostate pseudohyperplastic variant |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=136;epage=138;aulast=Dudani |
| work_keys_str_mv | AT sharmiladudani pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate AT ajaymalik pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate AT assandhu pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate AT nsmani pseudohyperplasticvariantofadenocarcinomaasacomponentofamethylcoaracemaseamacrnegativecarcinosarcomaoftheprostate |