Internalization of Recombinant Imiglucerase into Mouse Peritoneal Macrophages and L929 Mouse Fibroblasts

Internalization of Recombinant Imiglucerase into Mouse Peritoneal Macrophages and L929 Mouse Fibroblasts

Enzyme replacement therapy (ERT) is one of the most efficient treatments for lysosomal storage diseases. Type 1 Gaucher disease is caused by β-glucocerebrosidase enzyme deficiency, which may be compensated for by intravenous infusions of imiglucerase—a recombinant enzyme. Imiglucerase targets macrop...

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Bibliographic Details
Main Authors:	I. V. Lyagoskin, M. S. Pantyushenko, O. M. Strizhakova, N. K. Kudina, E. Yu. Prudnikova, P. V. Chichkanova, S. G. Abbasova
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2020-03-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	recombinant imiglucerase target cells peritoneal macrophages l929 mouse fibroblasts internalization
Online Access:	https://www.biopreparations.ru/jour/article/view/270

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