Novel Suicide Ligands of Tubulin Arrest Cancer Cells in S-Phase

It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis 1]. In this report, we challenge the established dogma by describing a unique mechanis...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ashley Davis, Jian-Dong Jiang, Kim M. Middleton, Yue Wang, Imre Weisz, Yi-He Ling, J. George Bekesi
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 1999-12-01
Schriftenreihe:Neoplasia: An International Journal for Oncology Research
Schlagworte:
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1476558699800037