Novel Suicide Ligands of Tubulin Arrest Cancer Cells in S-Phase
It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis 1]. In this report, we challenge the established dogma by describing a unique mechanis...
| Main Authors: | , , , , , , |
|---|---|
| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Elsevier
1999-12-01
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| סדרה: | Neoplasia: An International Journal for Oncology Research |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S1476558699800037 |