Novel Suicide Ligands of Tubulin Arrest Cancer Cells in S-Phase
It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis 1]. In this report, we challenge the established dogma by describing a unique mechanis...
| Principais autores: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Elsevier
1999-12-01
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| coleção: | Neoplasia: An International Journal for Oncology Research |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1476558699800037 |