A 92 protein inflammation panel performed on sonicate fluid differentiates periprosthetic joint infection from non-infectious causes of arthroplasty failure
Abstract Periprosthetic joint infection (PJI) is a major complication of total joint arthroplasty, typically necessitating surgical intervention and prolonged antimicrobial therapy. Currently, there is no perfect assay for PJI diagnosis. Proteomic profiling of sonicate fluid has the potential to dif...
Main Authors: | Cody R. Fisher, Harold I. Salmons, Jay Mandrekar, Kerryl E. Greenwood-Quaintance, Matthew P. Abdel, Robin Patel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-20444-9 |
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